Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Fndc9 homozygote female Early adult Viability Primary Screen Homozygous females viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=UC Davis female infertility Fndc9 homozygote female Early adult Fertility of Homozygous Knock-out Mice Gross Findings Female UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_FER_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_019_001&phenotyping_center=UC Davis male infertility Fndc9 homozygote male Early adult Fertility of Homozygous Knock-out Mice Gross Findings Male UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_FER_001_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_001_001&phenotyping_center=UC Davis hyperactivity Fndc9 homozygote female Early adult Open Field Whole arena average speed UC Davis IMPC 1.82E-20 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_009_001&phenotyping_center=UC Davis hyperactivity Fndc9 homozygote female Early adult Open Field Distance travelled - total UC Davis IMPC 1.87E-20 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_020_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_020_001&phenotyping_center=UC Davis hyperactivity Fndc9 homozygote female Early adult Open Field Center distance travelled UC Davis IMPC 1.38E-18 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_014_001&phenotyping_center=UC Davis hyperactivity Fndc9 homozygote female Early adult Open Field Periphery average speed UC Davis IMPC 9.82E-18 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_013_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_013_001&phenotyping_center=UC Davis hyperactivity Fndc9 homozygote female Early adult Open Field Periphery distance travelled UC Davis IMPC 1.31E-14 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_010_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_010_001&phenotyping_center=UC Davis decreased prepulse inhibition Fndc9 homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 UC Davis IMPC 5.66E-11 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=UC Davis increased total body fat amount Fndc9 homozygote female Early adult Body Composition (DEXA lean/fat) Fat/Body weight UC Davis IMPC 3.29E-10 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=UC Davis increased total body fat amount Fndc9 homozygote female Early adult Body Composition (DEXA lean/fat) Fat mass UC Davis IMPC 8.61E-10 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=UC Davis increased circulating alkaline phosphatase level Fndc9 homozygote male Early adult Clinical Chemistry Alkaline phosphatase UC Davis IMPC 1.89E-9 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=UC Davis increased circulating bilirubin level Fndc9 homozygote female Early adult Clinical Chemistry Total bilirubin UC Davis IMPC 4.04E-9 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_CBC_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_008_001&phenotyping_center=UC Davis decreased lean body mass Fndc9 homozygote female Early adult Body Composition (DEXA lean/fat) Lean/Body weight UC Davis IMPC 5.08E-8 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=UC Davis decreased lean body mass Fndc9 homozygote male Early adult Body Composition (DEXA lean/fat) Lean/Body weight UC Davis IMPC 7.3E-8 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=UC Davis decreased lean body mass Fndc9 homozygote male Early adult Body Composition (DEXA lean/fat) Lean mass UC Davis IMPC 7.47E-8 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_003_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_003_001&phenotyping_center=UC Davis increased total body fat amount Fndc9 homozygote male Early adult Body Composition (DEXA lean/fat) Fat/Body weight UC Davis IMPC 7.91E-8 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=UC Davis decreased lean body mass Fndc9 homozygote female Early adult Body Composition (DEXA lean/fat) Lean mass UC Davis IMPC 1.24E-7 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_003_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_003_001&phenotyping_center=UC Davis increased total body fat amount Fndc9 homozygote male Early adult Body Composition (DEXA lean/fat) Fat mass UC Davis IMPC 1.34E-7 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=UC Davis decreased prepulse inhibition Fndc9 homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global UC Davis IMPC 1.02E-6 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_ACS_037_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_037_001&phenotyping_center=UC Davis decreased grip strength Fndc9 homozygote male Early adult Grip Strength Forelimb and hindlimb grip strength measurement mean UC Davis IMPC 1.16E-6 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_GRS_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_009_001&phenotyping_center=UC Davis decreased startle reflex Fndc9 homozygote not_considered Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S UC Davis IMPC 1.71E-6 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_ACS_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_006_001&phenotyping_center=UC Davis decreased prepulse inhibition Fndc9 homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 UC Davis IMPC 6.12E-6 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=UC Davis decreased grip strength Fndc9 homozygote male Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight UC Davis IMPC 6.35E-6 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=UC Davis increased mean platelet volume Fndc9 homozygote not_considered Early adult Hematology Mean platelet volume UC Davis IMPC 9.55E-6 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_HEM_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_019_001&phenotyping_center=UC Davis decreased lymphocyte cell number Fndc9 homozygote female Early adult Hematology Lymphocyte differential count UC Davis IMPC 1.43E-5 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_HEM_031_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_031_001&phenotyping_center=UC Davis decreased bone mineral content Fndc9 homozygote not_considered Early adult Body Composition (DEXA lean/fat) BMC/Body weight UC Davis IMPC 4.58E-5 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_DXA_007_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_007_001&phenotyping_center=UC Davis hyperactivity Fndc9 homozygote not_considered Early adult Open Field Center average speed UC Davis IMPC 5.61E-5 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_017_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_017_001&phenotyping_center=UC Davis increased neutrophil cell number Fndc9 homozygote female Early adult Hematology Neutrophil differential count UC Davis IMPC 5.99E-5 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_HEM_029_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_029_001&phenotyping_center=UC Davis decreased thigmotaxis Fndc9 homozygote female Early adult Open Field Periphery permanence time UC Davis IMPC 9.48E-5 //www.mousephenotype.org/data/charts?accession=MGI:2443410&allele_accession_id=MGI:5708249&zygosity=homozygote¶meter_stable_id=IMPC_OFD_012_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_012_001&phenotyping_center=UC Davis