Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data small testis Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_024_002 small testis Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_024_002 female infertility Rspo1 homozygote female Early adult Fertility of Homozygous Knock-out Mice Gross Findings Female UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=IMPC_FER_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_019_001&phenotyping_center=UC Davis abnormal testis morphology Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_024_002 small testis Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_024_002 abnormal testis morphology Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_024_002 abnormal kidney morphology Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_017_002 abnormal testis morphology Rspo1 homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2183426/IMPC_PAT_024_002 abnormal vitreous body morphology Rspo1 homozygote female Early adult Eye Morphology Right vitreous humor thickness ICS IMPC 3.88E-10 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_087_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_087_001&phenotyping_center=ICS abnormal eye anterior chamber depth Rspo1 homozygote female Early adult Eye Morphology Left anterior chamber depth ICS IMPC 2.0E-9 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_067_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_067_001&phenotyping_center=ICS abnormal eye anterior chamber depth Rspo1 homozygote female Early adult Eye Morphology Right anterior chamber depth ICS IMPC 1.39E-8 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_061_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_061_001&phenotyping_center=ICS decreased total body fat amount Rspo1 homozygote male Early adult Body Composition (DEXA lean/fat) Fat/Body weight UC Davis IMPC 2.59E-8 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=UC Davis abnormal vitreous body morphology Rspo1 homozygote female Early adult Eye Morphology Left vitreous humour thickness ICS IMPC 8.28E-8 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_088_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_088_001&phenotyping_center=ICS decreased total retina thickness Rspo1 homozygote female Early adult Eye Morphology Right total retinal thickness ICS IMPC 2.73E-7 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_062_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_062_001&phenotyping_center=ICS increased lean body mass Rspo1 homozygote male Early adult Body Composition (DEXA lean/fat) Lean/Body weight UC Davis IMPC 1.34E-6 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=UC Davis decreased lean body mass Rspo1 homozygote female Early adult Body Composition (DEXA lean/fat) Lean mass ICS IMPC 2.0E-6 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_DXA_003_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_003_001&phenotyping_center=ICS abnormal retina outer nuclear layer morphology Rspo1 homozygote female Early adult Eye Morphology Left outer nuclear layer ICS IMPC 2.11E-6 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_070_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_070_001&phenotyping_center=ICS decreased brain weight Rspo1 homozygote male Early adult Organ Weight Brain weight UC Davis IMPC 4.27E-6 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=UCD_OWT_010_001&pipeline_stable_id=UCD_001&procedure_stable_id=UCD_OWT_001¶meter_stable_id=UCD_OWT_010_001&phenotyping_center=UC Davis abnormal retina outer nuclear layer morphology Rspo1 homozygote female Early adult Eye Morphology Right outer nuclear layer ICS IMPC 4.58E-6 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_064_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_064_001&phenotyping_center=ICS increased grip strength Rspo1 homozygote male Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight UC Davis IMPC 9.23E-6 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=UC Davis abnormal vibrissa morphology Rspo1 homozygote female Early adult Combined SHIRPA and Dysmorphology Vibrissae - appearance UC Davis IMPC 1.15E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=IMPC_CSD_024_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_024_001&phenotyping_center=UC Davis decreased total retina thickness Rspo1 homozygote female Early adult Eye Morphology Left total retinal thickness ICS IMPC 1.32E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_068_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_068_001&phenotyping_center=ICS increased bone mineral content Rspo1 homozygote male Early adult Body Composition (DEXA lean/fat) BMC/Body weight UC Davis IMPC 2.36E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5583071&zygosity=homozygote¶meter_stable_id=IMPC_DXA_007_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_007_001&phenotyping_center=UC Davis increased circulating alkaline phosphatase level Rspo1 homozygote male Early adult Clinical Chemistry Alkaline phosphatase ICS IMPC 3.44E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=ICS increased lymphocyte cell number Rspo1 homozygote female Early adult Hematology Lymphocyte cell count ICS IMPC 5.4E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_HEM_032_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_032_001&phenotyping_center=ICS increased circulating creatinine level Rspo1 homozygote female Early adult Clinical Chemistry Creatinine ICS IMPC 8.28E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_CBC_005_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_005_001&phenotyping_center=ICS decreased total retina thickness Rspo1 homozygote male Early adult Eye Morphology Right total retinal thickness ICS IMPC 8.71E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_EYE_062_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_062_001&phenotyping_center=ICS decreased lean body mass Rspo1 homozygote female Early adult Body Composition (DEXA lean/fat) Lean/Body weight ICS IMPC 8.94E-5 //www.mousephenotype.org/data/charts?accession=MGI:2183426&allele_accession_id=MGI:5766760&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=ICS_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=ICS