Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data enlarged spleen Helq homozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_016_002 abnormal testis morphology Helq homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_024_002 small kidney Helq homozygote female Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_017_002 female infertility Helq homozygote female Early adult Fertility of Homozygous Knock-out Mice Gross Findings Female UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_FER_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_019_001&phenotyping_center=UC Davis small kidney Helq homozygote female Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_017_002 male infertility Helq homozygote male Early adult Fertility of Homozygous Knock-out Mice Gross Findings Male UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_FER_001_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_001_001&phenotyping_center=UC Davis abnormal kidney morphology Helq homozygote female Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_017_002 abnormal testis morphology Helq homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_024_002 Testis - MPATH pathological process term hypoplasia Helq homozygote male Early adult Histopathology Testis - MPATH pathological process term UC Davis IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2176740?anatomy="Testis" abnormal kidney morphology Helq homozygote female Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_017_002 Ovary - MPATH pathological process term hypoplasia Helq homozygote female Early adult Histopathology Ovary - MPATH pathological process term UC Davis IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2176740?anatomy="Ovary" Testis - MPATH pathological process term atrophy Helq homozygote male Early adult Histopathology Testis - MPATH pathological process term UC Davis IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2176740?anatomy="Testis" Ovary - MPATH pathological process term atrophy Helq homozygote female Early adult Histopathology Ovary - MPATH pathological process term UC Davis IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2176740?anatomy="Ovary" small testis Helq homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_024_002 abnormal eye morphology Helq homozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_002_002 small testis Helq homozygote male Early adult Gross Pathology and Tissue Collection Testes UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_024_002 abnormal spleen morphology Helq homozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2176740/IMPC_PAT_016_002 increased total body fat amount Helq homozygote female Early adult Body Composition (DEXA lean/fat) Fat/Body weight UC Davis IMPC 1.07E-10 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=UC Davis decreased lean body mass Helq homozygote female Early adult Body Composition (DEXA lean/fat) Lean/Body weight UC Davis IMPC 1.54E-10 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=UC Davis decreased bone mineral content Helq homozygote female Early adult Body Composition (DEXA lean/fat) BMC/Body weight UC Davis IMPC 7.21E-10 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_DXA_007_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_007_001&phenotyping_center=UC Davis increased total body fat amount Helq homozygote female Early adult Body Composition (DEXA lean/fat) Fat mass UC Davis IMPC 2.96E-8 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=UC Davis decreased lean body mass Helq homozygote female Early adult Body Composition (DEXA lean/fat) Lean mass UC Davis IMPC 6.03E-7 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_DXA_003_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_003_001&phenotyping_center=UC Davis abnormal caudal vertebrae morphology Helq homozygote not_considered Early adult X-ray Number of caudal vertebrae UC Davis IMPC 1.19E-6 //www.mousephenotype.org/data/charts?accession=MGI:2176740&allele_accession_id=MGI:6362816&zygosity=homozygote¶meter_stable_id=IMPC_XRY_017_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_XRY_001¶meter_stable_id=IMPC_XRY_017_001&phenotyping_center=UC Davis