Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Patl1 homozygote male Early adult Viability Primary Screen Homozygous males viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=BCM unresponsive to tactile stimuli Patl1 homozygote female E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=homozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM unresponsive to tactile stimuli Patl1 homozygote male E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=homozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM preweaning lethality, complete penetrance Patl1 homozygote female Early adult Viability Primary Screen Homozygous females viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=BCM preweaning lethality, incomplete penetrance Patl1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=BCM unresponsive to tactile stimuli Patl1 heterozygote male E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM unresponsive to tactile stimuli Patl1 heterozygote female E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM decreased grip strength Patl1 heterozygote male Early adult Grip Strength Forelimb and hindlimb grip strength measurement mean BCM IMPC 1.03E-15 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_GRS_009_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_009_001&phenotyping_center=BCM decreased grip strength Patl1 heterozygote male Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight BCM IMPC 1.37E-12 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=BCM decreased grip strength Patl1 heterozygote male Early adult Grip Strength Forelimb grip strength measurement mean BCM IMPC 5.06E-8 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_GRS_008_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_008_001&phenotyping_center=BCM decreased prepulse inhibition Patl1 heterozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 BCM IMPC 1.18E-5 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=BCM decreased prepulse inhibition Patl1 heterozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 BCM IMPC 2.78E-5 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=BCM decreased grip strength Patl1 heterozygote male Early adult Grip Strength Forelimb grip strength normalised against body weight BCM IMPC 4.79E-5 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_GRS_010_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_010_001&phenotyping_center=BCM tremors Patl1 heterozygote not_considered Early adult Combined SHIRPA and Dysmorphology Tremor BCM IMPC 5.43E-5 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_030_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_030_001&phenotyping_center=BCM decreased fasting circulating glucose level Patl1 heterozygote male Early adult Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration BCM IMPC 6.92E-5 //www.mousephenotype.org/data/charts?accession=MGI:2147679&allele_accession_id=MGI:5574606&zygosity=heterozygote¶meter_stable_id=IMPC_IPG_010_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_010_001&phenotyping_center=BCM