Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data male infertility Wsb2 homozygote male Early adult Fertility of Homozygous Knock-out Mice Gross Findings Male HMGU IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_FER_001_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_001_001&phenotyping_center=HMGU female infertility Wsb2 homozygote female Early adult Fertility of Homozygous Knock-out Mice Gross Findings Female HMGU IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_FER_019_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_FER_001¶meter_stable_id=IMPC_FER_019_001&phenotyping_center=HMGU decreased total retina thickness Wsb2 homozygote female Early adult Eye Morphology Left total retinal thickness HMGU IMPC 1.08E-43 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_068_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_068_001&phenotyping_center=HMGU decreased total retina thickness Wsb2 homozygote female Early adult Eye Morphology Right total retinal thickness HMGU IMPC 8.68E-42 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_062_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_062_001&phenotyping_center=HMGU decreased total retina thickness Wsb2 homozygote male Early adult Eye Morphology Left total retinal thickness HMGU IMPC 1.54E-32 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_068_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_068_001&phenotyping_center=HMGU decreased total retina thickness Wsb2 homozygote male Early adult Eye Morphology Right total retinal thickness HMGU IMPC 1.34E-30 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_062_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_062_001&phenotyping_center=HMGU increased grip strength Wsb2 homozygote female Early adult Grip Strength Forelimb grip strength normalised against body weight HMGU IMPC 2.3E-12 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_GRS_010_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_010_001&phenotyping_center=HMGU abnormal tooth morphology Wsb2 homozygote female Early adult Combined SHIRPA and Dysmorphology Upper teeth appearance HMGU IMPC 3.49E-12 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CSD_069_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CSD_002¶meter_stable_id=IMPC_CSD_069_001&phenotyping_center=HMGU decreased respiratory quotient Wsb2 homozygote female Early adult Indirect Calorimetry Respiratory Exchange Ratio HMGU IMPC 2.12E-10 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CAL_017_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CAL_003¶meter_stable_id=IMPC_CAL_017_001&phenotyping_center=HMGU abnormal tooth morphology Wsb2 homozygote male Early adult Combined SHIRPA and Dysmorphology Upper teeth appearance HMGU IMPC 9.79E-10 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CSD_069_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CSD_002¶meter_stable_id=IMPC_CSD_069_001&phenotyping_center=HMGU decreased food intake Wsb2 homozygote female Early adult Indirect Calorimetry Total food intake HMGU IMPC 6.01E-9 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CAL_008_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CAL_003¶meter_stable_id=IMPC_CAL_008_001&phenotyping_center=HMGU increased circulating alkaline phosphatase level Wsb2 homozygote female Early adult Clinical Chemistry Alkaline phosphatase HMGU IMPC 2.45E-8 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=HMGU abnormal retina vasculature morphology Wsb2 homozygote female Early adult Eye Morphology Retinal Blood Vessels HMGU IMPC 2.62E-8 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_024_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_024_001&phenotyping_center=HMGU decreased vertical activity Wsb2 homozygote female Early adult Open Field Number of rears - total HMGU IMPC 4.09E-8 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_OFD_021_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_021_001&phenotyping_center=HMGU abnormal retina blood vessel morphology Wsb2 homozygote female Early adult Eye Morphology Retinal Blood Vessels Pattern HMGU IMPC 1.05E-7 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_026_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_026_001&phenotyping_center=HMGU hyperactivity Wsb2 homozygote female Early adult Open Field Whole arena resting time HMGU IMPC 2.82E-7 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_OFD_007_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_007_001&phenotyping_center=HMGU decreased food intake Wsb2 homozygote male Early adult Indirect Calorimetry Total food intake HMGU IMPC 4.08E-7 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CAL_008_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CAL_003¶meter_stable_id=IMPC_CAL_008_001&phenotyping_center=HMGU hyperactivity Wsb2 homozygote female Early adult Open Field Periphery resting time HMGU IMPC 1.25E-6 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_OFD_011_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_011_001&phenotyping_center=HMGU decreased heart rate Wsb2 homozygote female Early adult Echo HR HMGU IMPC 3.16E-6 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_ECH_013_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_ECH_001¶meter_stable_id=IMPC_ECH_013_001&phenotyping_center=HMGU decreased vertical activity Wsb2 homozygote male Early adult Open Field Number of rears - total HMGU IMPC 8.15E-6 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_OFD_021_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_021_001&phenotyping_center=HMGU decreased respiratory quotient Wsb2 homozygote male Early adult Indirect Calorimetry Respiratory Exchange Ratio HMGU IMPC 1.24E-5 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_CAL_017_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_CAL_003¶meter_stable_id=IMPC_CAL_017_001&phenotyping_center=HMGU decreased cardiac muscle contractility Wsb2 homozygote female Early adult Echo Fractional Shortening HMGU IMPC 4.52E-5 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_ECH_005_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_ECH_001¶meter_stable_id=IMPC_ECH_005_001&phenotyping_center=HMGU decreased heart rate Wsb2 homozygote male Early adult Echo HR HMGU IMPC 5.93E-5 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_ECH_013_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_ECH_001¶meter_stable_id=IMPC_ECH_013_001&phenotyping_center=HMGU increased grip strength Wsb2 homozygote female Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight HMGU IMPC 6.31E-5 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=HMGU abnormal retina vasculature morphology Wsb2 homozygote male Early adult Eye Morphology Retinal Blood Vessels HMGU IMPC 7.17E-5 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_EYE_024_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_024_001&phenotyping_center=HMGU decreased locomotor activity Wsb2 homozygote female Early adult Open Field Whole arena average speed HMGU IMPC 7.98E-5 //www.mousephenotype.org/data/charts?accession=MGI:2144041&allele_accession_id=MGI:5548747&zygosity=homozygote¶meter_stable_id=IMPC_OFD_009_001&pipeline_stable_id=HMGU_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_009_001&phenotyping_center=HMGU