Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data small spleen Nsd3 homozygote male Early adult Gross Pathology and Tissue Collection Spleen MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2142581/IMPC_PAT_016_002 preweaning lethality, incomplete penetrance Nsd3 homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell increased circulating alkaline phosphatase level Nsd3 homozygote male Early adult Clinical Chemistry Alkaline phosphatase MRC Harwell IMPC 4.25E-17 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=MRC Harwell increased circulating alkaline phosphatase level Nsd3 homozygote female Early adult Clinical Chemistry Alkaline phosphatase MRC Harwell IMPC 2.39E-11 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=MRC Harwell trunk curl Nsd3 heterozygote female Early adult Combined SHIRPA and Dysmorphology Trunk curl MRC Harwell IMPC 5.96E-9 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_038_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_038_001&phenotyping_center=MRC Harwell increased startle reflex Nsd3 homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S MRC Harwell IMPC 1.6E-8 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=homozygote¶meter_stable_id=IMPC_ACS_006_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_006_001&phenotyping_center=MRC Harwell tremors Nsd3 heterozygote male Early adult Combined SHIRPA and Dysmorphology Tremor MRC Harwell IMPC 2.7E-6 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_030_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_030_001&phenotyping_center=MRC Harwell increased total body fat amount Nsd3 heterozygote female Early adult Body Composition (DEXA lean/fat) Fat/Body weight MRC Harwell IMPC 5.94E-6 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=MRC Harwell abnormal snout morphology Nsd3 homozygote not_considered Early adult Combined SHIRPA and Dysmorphology Snout size MRC Harwell IMPC 2.72E-5 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=homozygote¶meter_stable_id=IMPC_CSD_028_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_028_001&phenotyping_center=MRC Harwell tremors Nsd3 heterozygote female Early adult Combined SHIRPA and Dysmorphology Tremor MRC Harwell IMPC 5.01E-5 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_030_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_030_001&phenotyping_center=MRC Harwell increased total body fat amount Nsd3 heterozygote not_considered Early adult Body Composition (DEXA lean/fat) Fat mass MRC Harwell IMPC 6.03E-5 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=MRC Harwell decreased exploration in new environment Nsd3 homozygote not_considered Early adult Combined SHIRPA and Dysmorphology Locomotor activity MRC Harwell IMPC 9.05E-5 //www.mousephenotype.org/data/charts?accession=MGI:2142581&allele_accession_id=MGI:5637114&zygosity=homozygote¶meter_stable_id=IMPC_CSD_032_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_032_001&phenotyping_center=MRC Harwell