Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Krit1 homozygote male Early adult Viability Primary Screen Homozygous males viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=UC Davis abnormal chorioallantoic fusion Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Chorioallantoic fusion UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_019_001&phenotyping_center=UC Davis abnormal pharyngeal arch morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Branchial arch morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_024_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_024_001&phenotyping_center=UC Davis enlarged heart Krit1 heterozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1930618/IMPC_PAT_006_002 abnormal heart morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Heart morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_058_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_058_001&phenotyping_center=UC Davis preweaning lethality, complete penetrance Krit1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=UC Davis abnormal neural tube closure Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Neural tube closure UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_027_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_027_001&phenotyping_center=UC Davis abnormal heart looping Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Heart looping UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_057_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_057_001&phenotyping_center=UC Davis abnormal heart looping Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Heart looping UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_057_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_057_001&phenotyping_center=UC Davis embryonic growth retardation Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Delayed embryonic development UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_063_001&phenotyping_center=UC Davis abnormal neural tube closure Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube closure UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_027_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_027_001&phenotyping_center=UC Davis embryonic lethality prior to tooth bud stage Krit1 homozygote not_considered E12.5 Viability E12.5 Secondary Screen Outcome UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_EVM_001_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EVM_001¶meter_stable_id=IMPC_EVM_001_001&phenotyping_center=UC Davis abnormal somite shape Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Somite Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_064_001&phenotyping_center=UC Davis abnormal pericardium morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Pericardium Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_006_001&phenotyping_center=UC Davis abnormal chorioallantoic fusion Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Chorioallantoic fusion UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_019_001&phenotyping_center=UC Davis abnormal optic vesicle formation Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Optic vesicle morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_061_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_061_001&phenotyping_center=UC Davis abnormal allantois morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Allantois Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_014_001&phenotyping_center=UC Davis abnormal left-right axis patterning Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Left-right axis patterning UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_065_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_065_001&phenotyping_center=UC Davis embryonic growth retardation Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Delayed embryonic development UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_063_001&phenotyping_center=UC Davis abnormal neural tube morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Neural tube morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=UC Davis abnormal embryo size Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Embryo Size UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_032_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_032_001&phenotyping_center=UC Davis abnormal embryo size Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Embryo Size UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_032_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_032_001&phenotyping_center=UC Davis abnormal pharyngeal arch morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Branchial arch morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_024_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_024_001&phenotyping_center=UC Davis abnormal left-right axis patterning Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Left-right axis patterning UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_065_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_065_001&phenotyping_center=UC Davis abnormal somite shape Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Somite Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_064_001&phenotyping_center=UC Davis abnormal eye morphology Krit1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1930618/IMPC_PAT_002_002 pallor Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Pallor UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_036_002&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_036_002&phenotyping_center=UC Davis abnormal allantois morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Allantois Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_014_001&phenotyping_center=UC Davis abnormal embryo turning Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Embryo turning UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_011_001&phenotyping_center=UC Davis abnormal blood vessel morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Vascular morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_066_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_066_001&phenotyping_center=UC Davis absent optic nerve Krit1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1930618/IMPC_PAT_002_002 preweaning lethality, complete penetrance Krit1 homozygote female Early adult Viability Primary Screen Homozygous females viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=UC Davis abnormal embryo turning Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Embryo turning UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_011_001&phenotyping_center=UC Davis abnormal optic vesicle formation Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Optic vesicle morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_061_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_061_001&phenotyping_center=UC Davis pallor Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Pallor UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_036_002&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_036_002&phenotyping_center=UC Davis abnormal pericardium morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Pericardium Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_006_001&phenotyping_center=UC Davis abnormal otic vesicle morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Otic vesicle morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_042_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_042_001&phenotyping_center=UC Davis abnormal heart morphology Krit1 heterozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1930618/IMPC_PAT_006_002 abnormal otic vesicle morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Otic vesicle morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_042_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_042_001&phenotyping_center=UC Davis abnormal neural tube morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=UC Davis abnormal heart morphology Krit1 homozygote male E9.5 Gross Morphology Embryo E9.5 Heart morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_058_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_058_001&phenotyping_center=UC Davis abnormal blood vessel morphology Krit1 homozygote female E9.5 Gross Morphology Embryo E9.5 Vascular morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=homozygote¶meter_stable_id=IMPC_GEL_066_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_066_001&phenotyping_center=UC Davis abnormal eye morphology Krit1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1930618/IMPC_PAT_002_002 decreased grip strength Krit1 heterozygote male Early adult Grip Strength Forelimb grip strength normalised against body weight UC Davis IMPC 1.63E-5 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=heterozygote¶meter_stable_id=IMPC_GRS_010_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_010_001&phenotyping_center=UC Davis increased circulating alanine transaminase level Krit1 heterozygote male Early adult Clinical Chemistry Alanine aminotransferase UC Davis IMPC 4.54E-5 //www.mousephenotype.org/data/charts?accession=MGI:1930618&allele_accession_id=MGI:5583067&zygosity=heterozygote¶meter_stable_id=IMPC_CBC_013_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_013_001&phenotyping_center=UC Davis