Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Notum homozygote female Early adult Viability Primary Screen Homozygous females viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=TCP Ear - inflammation Notum homozygote male Early adult Histopathology Ear - MPATH process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1924833?anatomy="Ear" abnormal brain morphology Notum homozygote male Early adult Gross Pathology and Tissue Collection Brain TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1924833/IMPC_PAT_001_002 abnormal kidney morphology Notum homozygote male Early adult Gross Pathology and Tissue Collection Kidney TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1924833/IMPC_PAT_017_002 small uterus Notum heterozygote female Late adult Gross Pathology and Tissue Collection Uterus TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1924833/TCPLA_PAT_029_002 abnormal uterus morphology Notum heterozygote female Early adult Gross Pathology and Tissue Collection Uterus TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1924833/IMPC_PAT_029_002 anophthalmia Notum homozygote female E18.5 Gross Morphology Embryo E18.5 Anophthalmia TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=homozygote¶meter_stable_id=IMPC_GEP_060_002&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_060_002&phenotyping_center=TCP preweaning lethality, incomplete penetrance Notum homozygote male Early adult Viability Primary Screen Homozygous males viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=TCP anophthalmia Notum homozygote male E18.5 Gross Morphology Embryo E18.5 Anophthalmia TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=homozygote¶meter_stable_id=IMPC_GEP_060_002&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_060_002&phenotyping_center=TCP Kidney - agenesis Notum homozygote male Early adult Histopathology Kidney - MPATH process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1924833?anatomy="Kidney" Tooth - developmental dysplasia Notum homozygote male Early adult Histopathology Tooth - MPATH process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1924833?anatomy="Tooth" small spleen Notum heterozygote female Late adult Gross Pathology and Tissue Collection Spleen TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1924833/TCPLA_PAT_016_002 preweaning lethality, incomplete penetrance Notum homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=TCP small ovary Notum heterozygote female Late adult Gross Pathology and Tissue Collection Ovary TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1924833/TCPLA_PAT_028_002 decreased exploration in new environment Notum heterozygote male Early adult Open Field Latency to center entry TCP IMPC 1.49E-8 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=heterozygote¶meter_stable_id=IMPC_OFD_018_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_018_001&phenotyping_center=TCP cataract Notum heterozygote not_considered Late adult Eye Morphology Lens Opacity TCP IMPC 2.36E-7 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=heterozygote¶meter_stable_id=TCPLA_EYE_017_001&pipeline_stable_id=TCPLA_001&procedure_stable_id=TCPLA_EYE_003¶meter_stable_id=TCPLA_EYE_017_001&phenotyping_center=TCP decreased grip strength Notum heterozygote female Late adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight TCP IMPC 4.86E-5 //www.mousephenotype.org/data/charts?accession=MGI:1924833&allele_accession_id=MGI:6156499&zygosity=heterozygote¶meter_stable_id=TCPLA_GRS_011_001&pipeline_stable_id=TCPLA_001&procedure_stable_id=TCPLA_GRS_001¶meter_stable_id=TCPLA_GRS_011_001&phenotyping_center=TCP