Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data increased circulating aspartate transaminase level Agl homozygote female Early adult Clinical Chemistry Aspartate aminotransferase MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_012_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_012_001&phenotyping_center=MRC Harwell increased circulating iron level Agl homozygote female Early adult Clinical Chemistry Iron MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_011_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_011_001&phenotyping_center=MRC Harwell decreased circulating glucose level Agl homozygote female Early adult Clinical Chemistry Glucose MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_018_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_018_001&phenotyping_center=MRC Harwell increased circulating alkaline phosphatase level Agl homozygote female Early adult Clinical Chemistry Alkaline phosphatase MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=MRC Harwell preweaning lethality, incomplete penetrance Agl homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell increased circulating alanine transaminase level Agl homozygote female Early adult Clinical Chemistry Alanine aminotransferase MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_013_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_013_001&phenotyping_center=MRC Harwell cataract Agl homozygote female Early adult Eye Morphology Lens Opacity MRC Harwell IMPC 7.11E-14 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_EYE_017_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_017_001&phenotyping_center=MRC Harwell impaired glucose tolerance Agl homozygote female Early adult Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve MRC Harwell IMPC 3.31E-11 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_IPG_012_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_012_001&phenotyping_center=MRC Harwell increased heart weight Agl homozygote female Early adult Organ Weight Heart weight MRC Harwell IMPC 1.68E-10 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_HWT_008_001&pipeline_stable_id=HRWL_001&procedure_stable_id=HRWL_OWT_001¶meter_stable_id=IMPC_HWT_008_001&phenotyping_center=MRC Harwell increased kidney weight Agl homozygote female Early adult Organ Weight Left kidney MRC Harwell IMPC 1.94E-9 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=HRWL_OWT_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=HRWL_OWT_001¶meter_stable_id=HRWL_OWT_002_001&phenotyping_center=MRC Harwell increased fasting circulating glucose level Agl homozygote female Early adult Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration MRC Harwell IMPC 2.97E-9 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_IPG_010_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_010_001&phenotyping_center=MRC Harwell decreased bone mineral content Agl homozygote female Early adult Body Composition (DEXA lean/fat) BMC/Body weight MRC Harwell IMPC 7.12E-9 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_DXA_007_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_007_001&phenotyping_center=MRC Harwell increased lean body mass Agl homozygote female Early adult Body Composition (DEXA lean/fat) Lean mass MRC Harwell IMPC 8.49E-9 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_DXA_003_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_003_001&phenotyping_center=MRC Harwell decreased total body fat amount Agl homozygote female Early adult Body Composition (DEXA lean/fat) Fat mass MRC Harwell IMPC 1.38E-7 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=MRC Harwell increased circulating bilirubin level Agl homozygote female Early adult Clinical Chemistry Total bilirubin MRC Harwell IMPC 8.69E-7 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_008_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_008_001&phenotyping_center=MRC Harwell increased circulating amylase level Agl homozygote female Early adult Clinical Chemistry Alpha-amylase MRC Harwell IMPC 1.39E-6 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_023_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_023_001&phenotyping_center=MRC Harwell decreased bone mineral content Agl homozygote female Early adult Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) MRC Harwell IMPC 2.56E-6 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_DXA_005_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_005_001&phenotyping_center=MRC Harwell decreased bone mineral density Agl homozygote female Early adult Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) MRC Harwell IMPC 4.41E-6 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_DXA_004_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_004_001&phenotyping_center=MRC Harwell cataract Agl homozygote male Early adult Eye Morphology Lens Opacity MRC Harwell IMPC 1.58E-5 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_EYE_017_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_017_001&phenotyping_center=MRC Harwell increased circulating creatine kinase level Agl homozygote female Early adult Clinical Chemistry Creatine kinase MRC Harwell IMPC 2.59E-5 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_028_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_028_001&phenotyping_center=MRC Harwell tremors Agl heterozygote not_considered Early adult Combined SHIRPA and Dysmorphology Tremor MRC Harwell IMPC 2.97E-5 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_030_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_030_001&phenotyping_center=MRC Harwell increased circulating cholesterol level Agl homozygote female Early adult Clinical Chemistry Total cholesterol MRC Harwell IMPC 6.1E-5 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CBC_015_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_015_001&phenotyping_center=MRC Harwell abnormal gait Agl homozygote male Early adult Combined SHIRPA and Dysmorphology Gait MRC Harwell IMPC 7.75E-5 //www.mousephenotype.org/data/charts?accession=MGI:1924809&allele_accession_id=MGI:5548686&zygosity=homozygote¶meter_stable_id=IMPC_CSD_033_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_033_001&phenotyping_center=MRC Harwell