Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data abnormal neural tube morphology Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Neural tube morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=BCM preweaning lethality, complete penetrance Opa1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=BCM abnormal neural tube closure Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Neural tube closure BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_027_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_027_001&phenotyping_center=BCM abnormal heart morphology Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Heart morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_058_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_058_001&phenotyping_center=BCM abnormal pharyngeal arch morphology Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Branchial arch morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_024_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_024_001&phenotyping_center=BCM abnormal pharyngeal arch morphology Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Branchial arch morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_024_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_024_001&phenotyping_center=BCM abnormal neural tube closure Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube closure BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_027_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_027_001&phenotyping_center=BCM abnormal embryo turning Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Embryo turning BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_011_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_011_001&phenotyping_center=BCM abnormal forebrain development Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Forebrain BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_028_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_028_001&phenotyping_center=BCM abnormal visceral yolk sac morphology Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Visceral yolk sac morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_018_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_018_001&phenotyping_center=BCM embryonic lethality prior to tooth bud stage Opa1 homozygote not_considered E12.5 Viability E12.5 Secondary Screen Outcome BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_EVM_001_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EVM_001¶meter_stable_id=IMPC_EVM_001_001&phenotyping_center=BCM preweaning lethality, complete penetrance Opa1 homozygote female Early adult Viability Primary Screen Homozygous females viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=BCM abnormal visceral yolk sac morphology Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Visceral yolk sac morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_018_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_018_001&phenotyping_center=BCM abnormal somite shape Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Somite Morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_064_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_064_001&phenotyping_center=BCM abnormal heart morphology Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Heart morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_058_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_058_001&phenotyping_center=BCM abnormal embryo size Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Embryo Size BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_032_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_032_001&phenotyping_center=BCM abnormal forebrain development Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Forebrain BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_028_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_028_001&phenotyping_center=BCM abnormal embryo turning Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Embryo turning BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_011_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_011_001&phenotyping_center=BCM abnormal embryo size Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Embryo Size BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_032_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_032_001&phenotyping_center=BCM abnormal neural tube morphology Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=BCM embryonic growth retardation Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Delayed embryonic development BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_063_001&phenotyping_center=BCM embryonic growth retardation Opa1 homozygote female E9.5 Gross Morphology Embryo E9.5 Delayed embryonic development BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_063_001&phenotyping_center=BCM abnormal somite shape Opa1 homozygote male E9.5 Gross Morphology Embryo E9.5 Somite Morphology BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_GEL_064_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_064_001&phenotyping_center=BCM preweaning lethality, complete penetrance Opa1 homozygote male Early adult Viability Primary Screen Homozygous males viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1921393&allele_accession_id=MGI:6384604&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=BCM