Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data embryonic lethality prior to organogenesis Pdss2 homozygote not_considered E9.5 Viability E9.5 Secondary Screen Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=homozygote¶meter_stable_id=IMPC_EVL_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EVL_001¶meter_stable_id=IMPC_EVL_001_001&phenotyping_center=MRC Harwell preweaning lethality, complete penetrance Pdss2 homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell embryonic lethality prior to tooth bud stage Pdss2 homozygote not_considered E12.5 Viability E12.5 Secondary Screen Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=homozygote¶meter_stable_id=IMPC_EVM_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EVM_001¶meter_stable_id=IMPC_EVM_001_001&phenotyping_center=MRC Harwell abnormal tooth morphology Pdss2 heterozygote male Early adult Combined SHIRPA and Dysmorphology Lower teeth appearance MRC Harwell IMPC 8.77E-9 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_070_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_070_001&phenotyping_center=MRC Harwell vertebral fusion Pdss2 heterozygote male Early adult X-ray Fusion of vertebrae MRC Harwell IMPC 2.03E-6 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_XRY_019_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_XRY_001¶meter_stable_id=IMPC_XRY_019_001&phenotyping_center=MRC Harwell thrombocytopenia Pdss2 heterozygote male Early adult Hematology Platelet count MRC Harwell IMPC 5.28E-6 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_008_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_008_001&phenotyping_center=MRC Harwell decreased thigmotaxis Pdss2 heterozygote not_considered Early adult Open Field Periphery permanence time MRC Harwell IMPC 6.1E-6 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_OFD_012_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_012_001&phenotyping_center=MRC Harwell increased total body fat amount Pdss2 heterozygote not_considered Early adult Body Composition (DEXA lean/fat) Fat/Body weight MRC Harwell IMPC 9.47E-6 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=MRC Harwell increased total body fat amount Pdss2 heterozygote male Early adult Body Composition (DEXA lean/fat) Fat mass MRC Harwell IMPC 5.82E-5 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=MRC Harwell decreased anxiety-related response Pdss2 heterozygote not_considered Early adult Open Field Percentage center movement time MRC Harwell IMPC 7.39E-5 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_OFD_050_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_050_001&phenotyping_center=MRC Harwell increased circulating bilirubin level Pdss2 heterozygote not_considered Early adult Clinical Chemistry Total bilirubin MRC Harwell IMPC 7.65E-5 //www.mousephenotype.org/data/charts?accession=MGI:1918615&allele_accession_id=MGI:5692707&zygosity=heterozygote¶meter_stable_id=IMPC_CBC_008_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_008_001&phenotyping_center=MRC Harwell