Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Mtx2 homozygote not_considered Early adult Viability Primary Screen Viability Outcome JAX IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1859652&allele_accession_id=MGI:6314758&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=JAX embryonic lethality prior to organogenesis Mtx2 homozygote not_considered E9.5 Viability E9.5 Secondary Screen Outcome JAX IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1859652&allele_accession_id=MGI:6314758&zygosity=homozygote¶meter_stable_id=IMPC_EVL_001_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_EVL_001¶meter_stable_id=IMPC_EVL_001_001&phenotyping_center=JAX decreased leukocyte cell number Mtx2 heterozygote male Early adult Hematology White blood cell count JAX IMPC 1.27E-7 //www.mousephenotype.org/data/charts?accession=MGI:1859652&allele_accession_id=MGI:6314758&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_001_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_001_001&phenotyping_center=JAX decreased circulating glucose level Mtx2 heterozygote not_considered Early adult Clinical Chemistry Glucose JAX IMPC 1.05E-5 //www.mousephenotype.org/data/charts?accession=MGI:1859652&allele_accession_id=MGI:6314758&zygosity=heterozygote¶meter_stable_id=IMPC_CBC_018_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_018_001&phenotyping_center=JAX increased bone mineral density Mtx2 heterozygote female Early adult Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) JAX IMPC 1.37E-5 //www.mousephenotype.org/data/charts?accession=MGI:1859652&allele_accession_id=MGI:6314758&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_004_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_004_001&phenotyping_center=JAX increased bone mineral density Mtx2 heterozygote male Early adult Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) JAX IMPC 3.6E-5 //www.mousephenotype.org/data/charts?accession=MGI:1859652&allele_accession_id=MGI:6314758&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_004_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_004_001&phenotyping_center=JAX