Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data Liver - lipid deposition Smc3 heterozygote male Early adult Histopathology Liver - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Liver" Liver - lipid deposition Smc3 heterozygote male Early adult Histopathology Liver - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Liver" Brain - process of degenerative change Smc3 heterozygote male Early adult Histopathology Brain - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Brain" Brain - developmental and structural abnormality Smc3 heterozygote male Early adult Histopathology Brain - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Brain" preweaning lethality, complete penetrance Smc3 homozygote not_considered Early adult Viability Primary Screen Viability Outcome WTSI IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=MGP_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=WTSI Liver - lipid deposition Smc3 heterozygote female Early adult Histopathology Liver - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Liver" Liver - lipid deposition Smc3 heterozygote female Early adult Histopathology Liver - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Liver" Brain - process of degenerative change Smc3 heterozygote male Early adult Histopathology Brain - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Brain" Brain - developmental and structural abnormality Smc3 heterozygote male Early adult Histopathology Brain - MPATH process term WTSI IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1339795?anatomy="Brain" decreased body weight Smc3 heterozygote female Early adult Heart Dissection Body Weight WTSI MGP 1.41E-11 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_020_001_001&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_020_001¶meter_stable_id=M-G-P_020_001_001&phenotyping_center=WTSI decreased body weight Smc3 heterozygote female Early adult Grip Strength Body weight WTSI MGP 2.19E-8 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_009_001_003&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_009_001¶meter_stable_id=M-G-P_009_001_003&phenotyping_center=WTSI decreased body weight Smc3 heterozygote female Early adult Dexa-scan analysis Weight WTSI MGP 5.58E-8 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_005_001_001&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_005_001¶meter_stable_id=M-G-P_005_001_001&phenotyping_center=WTSI decreased body weight Smc3 heterozygote female Early adult Hot Plate Body Weight WTSI MGP 4.85E-7 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_012_001_005&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_012_001¶meter_stable_id=M-G-P_012_001_005&phenotyping_center=WTSI abnormal coat/hair pigmentation Smc3 heterozygote male Early adult Dysmorphology Coat colouration WTSI MGP 2.64E-6 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_026_001_004&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_026_001¶meter_stable_id=M-G-P_026_001_004&phenotyping_center=WTSI decreased lean body mass Smc3 heterozygote male Early adult Dexa-scan analysis Lean Mass WTSI MGP 4.25E-6 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_005_001_003&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_005_001¶meter_stable_id=M-G-P_005_001_003&phenotyping_center=WTSI abnormal coat/hair pigmentation Smc3 heterozygote female Early adult Dysmorphology Coat colouration WTSI MGP 6.74E-6 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_026_001_004&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_026_001¶meter_stable_id=M-G-P_026_001_004&phenotyping_center=WTSI decreased lean body mass Smc3 heterozygote female Early adult Dexa-scan analysis Lean Mass WTSI MGP 2.12E-5 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_005_001_003&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_005_001¶meter_stable_id=M-G-P_005_001_003&phenotyping_center=WTSI decreased body weight Smc3 heterozygote male Early adult Dexa-scan analysis Weight WTSI MGP 3.17E-5 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_005_001_001&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_005_001¶meter_stable_id=M-G-P_005_001_001&phenotyping_center=WTSI decreased bone mineral content Smc3 heterozygote male Early adult Dexa-scan analysis Bone Mineral Content WTSI MGP 4.7E-5 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_005_001_005&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_005_001¶meter_stable_id=M-G-P_005_001_005&phenotyping_center=WTSI abnormal snout morphology Smc3 heterozygote not_considered Early adult Dysmorphology Snout morphology WTSI MGP 6.24E-5 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_026_001_011&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_026_001¶meter_stable_id=M-G-P_026_001_011&phenotyping_center=WTSI decreased body length Smc3 heterozygote male Early adult Dexa-scan analysis Body Length WTSI MGP 6.35E-5 //www.mousephenotype.org/data/charts?accession=MGI:1339795&allele_accession_id=MGI:4434007&zygosity=heterozygote¶meter_stable_id=M-G-P_005_001_006&pipeline_stable_id=M-G-P_001&procedure_stable_id=M-G-P_005_001¶meter_stable_id=M-G-P_005_001_006&phenotyping_center=WTSI