Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data increased circulating alkaline phosphatase level Itsn1 homozygote female Early adult Clinical Chemistry Alkaline phosphatase MRC Harwell IMPC 2.22E-17 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=MRC Harwell increased circulating alkaline phosphatase level Itsn1 homozygote male Early adult Clinical Chemistry Alkaline phosphatase MRC Harwell IMPC 4.55E-17 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=MRC Harwell abnormal skin coloration Itsn1 homozygote female Early adult Combined SHIRPA and Dysmorphology Skin color - front paws MRC Harwell IMPC 2.76E-11 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CSD_059_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_059_001&phenotyping_center=MRC Harwell abnormal skin coloration Itsn1 homozygote female Early adult Combined SHIRPA and Dysmorphology Skin color - back paws MRC Harwell IMPC 2.76E-11 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CSD_060_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_060_001&phenotyping_center=MRC Harwell increased circulating iron level Itsn1 homozygote female Early adult Clinical Chemistry Iron MRC Harwell IMPC 2.49E-10 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_011_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_011_001&phenotyping_center=MRC Harwell limb grasping Itsn1 homozygote male Early adult Combined SHIRPA and Dysmorphology Limb grasp MRC Harwell IMPC 1.04E-8 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CSD_039_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_039_001&phenotyping_center=MRC Harwell increased circulating amylase level Itsn1 homozygote male Early adult Clinical Chemistry Alpha-amylase MRC Harwell IMPC 1.9E-8 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_023_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_023_001&phenotyping_center=MRC Harwell decreased exploration in new environment Itsn1 heterozygote female Early adult Combined SHIRPA and Dysmorphology Locomotor activity MRC Harwell IMPC 6.08E-7 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_032_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_032_001&phenotyping_center=MRC Harwell abnormal gait Itsn1 homozygote female Early adult Combined SHIRPA and Dysmorphology Gait MRC Harwell IMPC 1.26E-5 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CSD_033_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_033_001&phenotyping_center=MRC Harwell increased circulating total protein level Itsn1 homozygote male Early adult Clinical Chemistry Total protein MRC Harwell IMPC 2.0E-5 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_006_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_006_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Itsn1 homozygote not_considered Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 MRC Harwell IMPC 2.57E-5 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=MRC Harwell increased circulating total protein level Itsn1 homozygote female Early adult Clinical Chemistry Total protein MRC Harwell IMPC 3.6E-5 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_006_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_006_001&phenotyping_center=MRC Harwell increased circulating serum albumin level Itsn1 homozygote male Early adult Clinical Chemistry Albumin MRC Harwell IMPC 5.85E-5 //www.mousephenotype.org/data/charts?accession=MGI:1338069&allele_accession_id=MGI:6257669&zygosity=homozygote¶meter_stable_id=IMPC_CBC_007_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_007_001&phenotyping_center=MRC Harwell