Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data enlarged heart Tnfrsf1a homozygote male Early adult Gross Pathology and Tissue Collection Heart CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1314884/IMPC_PAT_006_002 abnormal skin morphology Tnfrsf1a homozygote female Early adult Gross Pathology and Tissue Collection Skin CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1314884/IMPC_PAT_021_002 abnormal heart morphology Tnfrsf1a homozygote male Early adult Gross Pathology and Tissue Collection Heart CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1314884/IMPC_PAT_006_002 abnormal skin morphology Tnfrsf1a homozygote female Early adult Gross Pathology and Tissue Collection Skin CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1314884/IMPC_PAT_021_002 abnormal skin morphology Tnfrsf1a homozygote female Early adult Gross Pathology and Tissue Collection Skin CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1314884/IMPC_PAT_021_002 increased lymphocyte cell number Tnfrsf1a homozygote male Early adult Hematology Lymphocyte cell count MRC Harwell IMPC 1.6E-21 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=IMPC_HEM_032_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_032_001&phenotyping_center=MRC Harwell increased leukocyte cell number Tnfrsf1a homozygote male Early adult Hematology White blood cell count MRC Harwell IMPC 1.77E-18 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=IMPC_HEM_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_001_001&phenotyping_center=MRC Harwell increased large unstained cell number Tnfrsf1a homozygote female Late adult Hematology Large Unstained Cell (LUC) count MRC Harwell IMPC 2.78E-13 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_039_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_039_001&phenotyping_center=MRC Harwell increased lymphocyte cell number Tnfrsf1a homozygote female Late adult Hematology Lymphocyte cell count MRC Harwell IMPC 5.27E-11 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_032_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_032_001&phenotyping_center=MRC Harwell increased large unstained cell number Tnfrsf1a homozygote male Late adult Hematology Large Unstained Cell (LUC) count MRC Harwell IMPC 6.9E-11 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_039_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_039_001&phenotyping_center=MRC Harwell increased leukocyte cell number Tnfrsf1a homozygote female Late adult Hematology White blood cell count MRC Harwell IMPC 6.1E-10 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_001_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_001_001&phenotyping_center=MRC Harwell increased large unstained cell number Tnfrsf1a homozygote male Early adult Hematology Large Unstained Cell (LUC) count MRC Harwell IMPC 1.66E-9 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=IMPC_HEM_039_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_039_001&phenotyping_center=MRC Harwell increased eosinophil cell number Tnfrsf1a homozygote male Early adult Hematology Eosinophil cell count MRC Harwell IMPC 2.45E-9 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=IMPC_HEM_036_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_036_001&phenotyping_center=MRC Harwell increased basophil cell number Tnfrsf1a homozygote male Late adult Hematology Basophil cell count MRC Harwell IMPC 1.47E-8 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_037_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_037_001&phenotyping_center=MRC Harwell increased lymphocyte cell number Tnfrsf1a homozygote male Late adult Hematology Lymphocyte cell count MRC Harwell IMPC 3.39E-8 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_032_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_032_001&phenotyping_center=MRC Harwell increased leukocyte cell number Tnfrsf1a homozygote male Late adult Hematology White blood cell count MRC Harwell IMPC 1.6E-7 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_001_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_001_001&phenotyping_center=MRC Harwell increased lymphocyte cell number Tnfrsf1a homozygote male Late adult Hematology Lymphocyte cell count MRC Harwell IMPC 1.42E-6 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_032_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_032_001&phenotyping_center=MRC Harwell increased leukocyte cell number Tnfrsf1a homozygote male Late adult Hematology White blood cell count MRC Harwell IMPC 1.84E-6 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_001_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_001_001&phenotyping_center=MRC Harwell increased basophil cell number Tnfrsf1a homozygote female Late adult Hematology Basophil cell count MRC Harwell IMPC 2.47E-6 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_037_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_037_001&phenotyping_center=MRC Harwell increased neutrophil cell number Tnfrsf1a homozygote male Early adult Hematology Neutrophil differential count CCP-IMG IMPC 5.33E-6 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:7426125&zygosity=homozygote¶meter_stable_id=IMPC_HEM_029_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_029_001&phenotyping_center=CCP-IMG increased large unstained cell number Tnfrsf1a homozygote female Late adult Hematology Large Unstained Cell (LUC) differential count MRC Harwell IMPC 6.32E-6 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_040_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_040_001&phenotyping_center=MRC Harwell increased basophil cell number Tnfrsf1a homozygote male Early adult Hematology Basophil cell count MRC Harwell IMPC 9.68E-6 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=IMPC_HEM_037_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_037_001&phenotyping_center=MRC Harwell increased NK cell number Tnfrsf1a homozygote not_considered Early adult Immunophenotyping NK cells (Panel A) - % of live leukocytes (Panel A) CCP-IMG IMPC 1.47E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:7426125&zygosity=homozygote¶meter_stable_id=IMPC_IMM_005_002&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_IMM_002¶meter_stable_id=IMPC_IMM_005_002&phenotyping_center=CCP-IMG decreased monocyte cell number Tnfrsf1a homozygote female Late adult Hematology Monocyte differential count MRC Harwell IMPC 1.56E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_033_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_033_001&phenotyping_center=MRC Harwell decreased neutrophil cell number Tnfrsf1a homozygote female Late adult Hematology Neutrophil differential count MRC Harwell IMPC 2.3E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_029_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_029_001&phenotyping_center=MRC Harwell increased neutrophil cell number Tnfrsf1a homozygote male Early adult Hematology Neutrophil cell count CCP-IMG IMPC 2.35E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:7426125&zygosity=homozygote¶meter_stable_id=IMPC_HEM_030_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_030_001&phenotyping_center=CCP-IMG increased effector memory CD8-positive, alpha-beta T cell number Tnfrsf1a homozygote male Early adult Immunophenotyping Effector CD8+ T cells - % of live leukocytes (Panel A) CCP-IMG IMPC 2.46E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:7426125&zygosity=homozygote¶meter_stable_id=IMPC_IMM_032_002&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_IMM_002¶meter_stable_id=IMPC_IMM_032_002&phenotyping_center=CCP-IMG increased grip strength Tnfrsf1a homozygote not_considered Late adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight MRC Harwell IMPC 2.75E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_GRS_011_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_GRS_001¶meter_stable_id=HRWLLA_GRS_011_001&phenotyping_center=MRC Harwell increased eosinophil cell number Tnfrsf1a homozygote male Late adult Hematology Eosinophil cell count MRC Harwell IMPC 3.16E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_HEM_036_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_HEM_002¶meter_stable_id=HRWLLA_HEM_036_001&phenotyping_center=MRC Harwell increased grip strength Tnfrsf1a homozygote not_considered Late adult Grip Strength Forelimb grip strength normalised against body weight MRC Harwell IMPC 5.13E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_GRS_010_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_GRS_001¶meter_stable_id=HRWLLA_GRS_010_001&phenotyping_center=MRC Harwell decreased circulating calcium level Tnfrsf1a homozygote male Late adult Clinical Chemistry Calcium MRC Harwell IMPC 6.5E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=HRWLLA_CBC_009_001&pipeline_stable_id=HRWLLA_001&procedure_stable_id=HRWLLA_CBC_002¶meter_stable_id=HRWLLA_CBC_009_001&phenotyping_center=MRC Harwell increased basophil cell number Tnfrsf1a homozygote female Early adult Hematology Basophil cell count MRC Harwell IMPC 7.47E-5 //www.mousephenotype.org/data/charts?accession=MGI:1314884&allele_accession_id=MGI:5780574&zygosity=homozygote¶meter_stable_id=IMPC_HEM_037_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_037_001&phenotyping_center=MRC Harwell