Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Abce1 homozygote female Early adult Viability Primary Screen Homozygous females viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=TCP Eye - MPATH pathological process term hyperplasia Abce1 heterozygote female Early adult Histopathology Eye - MPATH pathological process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1195458?anatomy="Eye" embryonic lethality prior to organogenesis Abce1 homozygote not_considered E9.5 Viability E9.5 Secondary Screen Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:6120699&zygosity=homozygote¶meter_stable_id=IMPC_EVL_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EVL_001¶meter_stable_id=IMPC_EVL_001_001&phenotyping_center=MRC Harwell enlarged lymph nodes Abce1 heterozygote male Early adult Gross Pathology and Tissue Collection Lymph node TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1195458/IMPC_PAT_020_002 preweaning lethality, complete penetrance Abce1 homozygote male Early adult Viability Primary Screen Homozygous males viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=TCP Skin - MPATH pathological process term extracellular matrix deposition Abce1 heterozygote male Early adult Histopathology Skin - MPATH pathological process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1195458?anatomy="Skin" abnormal seminal vesicle morphology Abce1 heterozygote male Early adult Gross Pathology and Tissue Collection Seminal vesicle TCP IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1195458/IMPC_PAT_027_002 preweaning lethality, complete penetrance Abce1 homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:6120699&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell preweaning lethality, complete penetrance Abce1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=TCP Skin - MPATH pathological entity term hamartoma Abce1 heterozygote male Early adult Histopathology Skin - MPATH pathological entity term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1195458?anatomy="Skin" Skin - MPATH pathological process term hydropic degeneration Abce1 heterozygote male Early adult Histopathology Skin - MPATH pathological process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1195458?anatomy="Skin" increased large unstained cell number Abce1 heterozygote male Early adult Hematology Large Unstained Cell (LUC) count MRC Harwell IMPC 1.57E-9 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:6120699&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_039_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_039_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Abce1 heterozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI4 TCP IMPC 2.44E-7 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_036_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_036_001&phenotyping_center=TCP increased neutrophil cell number Abce1 heterozygote male Early adult Hematology Neutrophil cell count TCP IMPC 4.3E-7 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_030_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_030_001&phenotyping_center=TCP decreased prepulse inhibition Abce1 heterozygote not_considered Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 TCP IMPC 4.96E-6 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=TCP decreased prepulse inhibition Abce1 heterozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global TCP IMPC 1.01E-5 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_037_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_037_001&phenotyping_center=TCP decreased circulating creatinine level Abce1 heterozygote female Early adult Clinical Chemistry Creatinine MRC Harwell IMPC 2.48E-5 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:6120699&zygosity=heterozygote¶meter_stable_id=IMPC_CBC_005_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_005_001&phenotyping_center=MRC Harwell anophthalmia Abce1 heterozygote not_considered Early adult Eye Morphology Eye MRC Harwell IMPC 4.38E-5 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:6120699&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_001_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Abce1 heterozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI1 TCP IMPC 6.1E-5 //www.mousephenotype.org/data/charts?accession=MGI:1195458&allele_accession_id=MGI:5696882&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_033_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_033_001&phenotyping_center=TCP