Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Npc1 homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1097712&allele_accession_id=MGI:5636924&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell decreased exploration in new environment Npc1 heterozygote female Early adult Combined SHIRPA and Dysmorphology Locomotor activity MRC Harwell IMPC 1.6E-6 //www.mousephenotype.org/data/charts?accession=MGI:1097712&allele_accession_id=MGI:5636924&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_032_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_032_001&phenotyping_center=MRC Harwell increased monocyte cell number Npc1 heterozygote male Early adult FACs Analysis Monocyte gate MRC Harwell EuroPhenome 1.5E-5 //www.mousephenotype.org/data/charts?accession=MGI:1097712&allele_accession_id=MGI:4436617&zygosity=heterozygote¶meter_stable_id=ESLIM_018_001_009&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_018_001¶meter_stable_id=ESLIM_018_001_009&phenotyping_center=MRC Harwell increased startle reflex Npc1 heterozygote male Early adult Acoustic Startle&PPI PP3 + pulse startle magnitude MRC Harwell EuroPhenome 4.52E-5 //www.mousephenotype.org/data/charts?accession=MGI:1097712&allele_accession_id=MGI:4436617&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_009&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_009&phenotyping_center=MRC Harwell