Fam161atm1b(KOMP)Wtsi
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.00149
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0160
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Hole-board Exploration / Holepoke sequence
|
HOM
|
189f:162m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Light sleep bout lengths standard deviation
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.953
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Activity (body position)
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Head bobbing
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Percent time in light
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.913
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.111
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Trunk curl
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.430
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Side changes
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0567
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Hole-board Exploration / Total holepokes
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
4.91×10-05
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Dark sleep bout lengths mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.182
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Unexpected behaviors
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
5f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.435
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.903
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Light side time spent
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.984
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery distance travelled
|
HOM
|
8f:8m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.00738
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Whole arena resting time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00604
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Aggression
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Number of Rears
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Time mobile light side
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.168
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement mean
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
8.87×10-06
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Startle response
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Breath rate during sleep standard deviation
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0496
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Percentage center time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.430
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Distance travelled
|
HOM
|
32f:32m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - BN
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Vocalization
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.619
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Time immobile
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
1.83×10-05
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3_S
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Touch escape
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep daily percent
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.761
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Dark side time spent
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.984
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement mean
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
8.22×10-06
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep light phase percent
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.175
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Number of rears - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.384
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
18f:18m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength measurement
|
HOM
|
9f:6m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Latency to fall
|
HOM
|
45f:40m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Tail Suspension / Latency to immobility
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, including Weight
|
0.661
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Peak wake with respect to dark onset median
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.194
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb grip strength normalised against body weight
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
3.88×10-05
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Locomotor activity
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.363
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tail elevation
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2_S
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery average speed
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0436
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Time mobile dark side
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.639
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Fecal boli
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.679
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Contact righting
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep dark phase percent
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.103
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
3f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength normalised against body weight
|
HOM
|
6f:6m
|
Linear Mixed Model framework, LME, not including Weight
|
0.000165
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
9f:6m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Grip Strength / Forelimb and hindlimb grip strength measurement
|
HOM
|
18f:18m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Distance travelled - total
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0160
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Breath rate during sleep mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.0560
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Periphery permanence time
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.430
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Gait
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Learning slope
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.0212
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
5f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.214
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.905
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4
|
HOM
|
1f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
5f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.764
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.987
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep bout lengths mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.364
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Tremor
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
1.00
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
5f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, not including Weight
|
0.0974
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, including Weight
|
0.950
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
4f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
0.00368
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S
|
HOM
|
5f:4m
|
Linear Mixed Model framework, LME, not including Weight
|
4.13×10-07
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Latency to first transition into dark
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.919
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Learning difference
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.00282
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
1f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4
|
HOM
|
5f:4m
|
Linear Model Using Generalized Least Squares framework, GLS, including Weight
|
0.185
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
4f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP3
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Limb grasp
|
HOM
|
8f:8m
|
Fisher Exact Test framework
|
0.0132
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Dark sleep bout lengths standard deviation
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.451
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
1f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP4_S
|
HOM
|
5f:4m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Light sleep bout lengths mean
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.777
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Combined SHIRPA and Dysmorphology / Transfer arousal
|
HOM
|
8f:8m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Sleep bout lengths standard deviation
|
HOM
|
7f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.861
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Light-Dark Test / Percent time in dark
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.913
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Sleep Wake / Activity onset with respect to dark onset median
|
HOM
|
2f:2m
|
|
|
NotProcessed |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Rotarod / Average duration
|
HOM
|
9f:8m
|
Linear Mixed Model framework, LME, including Weight
|
0.549
|
Successful |
Fam161atm1b(KOMP)Wtsi
|
JAX
|
Open Field - centre start / Center distance travelled
|
HOM
|
8f:8m
|
Linear Mixed Model framework, LME, not including Weight
|
0.960
|
Successful |