All data for Ppil3

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector gd cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell number HOM 7f:7m 0.00520 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 0.0499 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.106 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Indirect Calorimetry / Total food intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0322 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 0f:7m 0.232 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0181 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Bone Mineral Density HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of DC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / LDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0117 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Height HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Calcium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00731 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 0.117 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 0.0285 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0628 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Macrophages - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.121 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Potassium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00126 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Myeloid cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 0f:7m 0.186 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Phosphorus HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.964 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.679 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / B1a cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Triglycerides HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0706 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.172 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 0.0192 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m 0.306 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 2f:2m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 0.618 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0633 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.608 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Sodium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0307 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Femoral Microradiography / Femur Length HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:7m Fisher Exact Test framework 0.123 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00385 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 1.34×10-06 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Granulocytes - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of NK cellls HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total B2 cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage HOM 7f:7m 0.345 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Alpha-amylase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00612 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Iron HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.288 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Magnesium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.152 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number HOM 7f:7m 0.0496 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Salmonella Challenge / Pre-Day 14 Death HOM 4f:0m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 2f:2m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0745 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Three-point Bend / Energy Dissipated Prior to Fracture HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number HOM 7f:7m 0.309 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Free fatty acids HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 1.28×10-05 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.273 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 0f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0153 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.171 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage HOM 7f:7m 0.309 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of lymphocytes HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 6.64×10-06 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 0.651 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell number HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Total B cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0594 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total DC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m 0.0544 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 4.99×10-05 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number HOM 7f:7m 0.00520 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 2f:2m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage HOM 7f:7m 0.306 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Glucose HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.733 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 2f:2m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Chloride HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0200 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.675 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number HOM 7f:7m 0.0574 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000496 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0281 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Alanine aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.329 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Eosinophils - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatinine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.421 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Thickness (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.940 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number HOM 7f:7m 0.306 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of lymphocytes HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.433 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific total IgG HOM 4f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.451 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatine kinase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0501 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number HOM 7f:7m 0.306 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m 0.0535 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.309 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+ HOM 3f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Three-point Bend / Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Thyroxine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.196 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Indirect Calorimetry / Total water intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0348 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 0f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage HOM 7f:7m 0.0535 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Spacing (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 0.299 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Total protein HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.395 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.191 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m 0.00413 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Three-point Bend / Fracture Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number HOM 7f:7m 0.0509 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Aspartate aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00225 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.684 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number HOM 7f:7m 0.0496 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of cDC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Glycerol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00976 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.353 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number HOM 7f:7m 0.313 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage HOM 7f:7m 0.345 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.764 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Monocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Three-point Bend / Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Thickness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.228 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number HOM 7f:7m 0.306 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Plasma cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 0f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 0f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Total cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 1.53×10-07 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m 0.0509 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.964 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.932 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG1 HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0770 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total ab T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_005_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+ HOM 3f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Femoral Microradiography / Femoral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of cDC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Number (mm-1) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Granulocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Number of digits HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 3f:0m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 0f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+ HOM 3f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Fructosamine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.215 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 0f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 3f:0m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00603 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Internal Diameter HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of NK cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number HOM 7f:7m 0.0496 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG2 HOM 4f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.342 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 2f:2m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00722 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.471 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Total bilirubin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.951 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of DC HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0117 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m 0.0561 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00152 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage HOM 7f:7m 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 2f:2m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+ HOM 3f:3m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Three-point Bend / Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Ppil3tm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD4+ HOM 6f:6m Manual 1.00 Success
Ppil3tm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppil3tm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data

Download data as: TSV XLS

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