Experiment details for alleles of Btbd9 | International Mouse Phenotyping Consortium

Allele	Center	Procedure / Parameter	Zygosity	Mutants	Statistical Method	P Value	Status
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Forelimb digit - size	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Tail - thickness	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Alanine aminotransferase	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.462	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Coat - hair distribution - back	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Bulging eye	HOM	8f:6m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Echo / LVPWd	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.0935	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Lipase	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.951	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Forelimb nail - shape	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / RR	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.384	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Skin texture - whole body	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Trunk curl	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Creatinine	HOM	7f:6m	Linear Mixed Model framework, LME, including Weight	0.0332	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Iris/Pupil	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Cartilage tissue	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Cartilage tissue	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Number of thoracic vertebrae	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Striatum	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Striatum	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Hematology / Mean cell hemoglobin concentration	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.975	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Sublingual Gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Sublingual Gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Indirect Calorimetry / Body weight before experiment	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Radius	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Corneal deposits	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Indirect Calorimetry / Total food intake	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.00532	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Fibula	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Hematology / Mean platelet volume	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.000123	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Percentage center time	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.245	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Shape of vertebrae	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / 6kHz-evoked ABR Threshold	HOM	4f:3m	Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)	0.0370	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Diaphragm	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Diaphragm	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Brachydactyly	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Body Composition (DEXA lean/fat) / Body length	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	2.60×10^-05	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Peyers Patch	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Peyers Patch	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Vibrissae - presence	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Small Intestine	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Small Intestine	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Lower teeth appearance	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Scapulae	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Lens Opacity	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Skin texture - back paws	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Number of Rears	HOM	32f:28m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Forelimbs - shape	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Parathyroid gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Parathyroid gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Retinal Structure	HOM	8f:6m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Skin	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Skin	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Thalamus	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Periphery distance travelled	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.708	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Lymph Node	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Lymph Node	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Esophagus	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Esophagus	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Retina (combined)	HOM	8f:6m	Fisher Exact Test framework	0.238	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Zygomatic bone	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Pancreas	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Pancreas	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Calcium	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.375	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Echo / HR	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.197	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Percentage center movement time	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.497	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Shape of ribs	HOM	5f:4m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Tail elevation	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Contact righting	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / Number of signals	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Skin color - ear	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Hematology / Hematocrit	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.173	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Hindlimb nail - number	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Grip Strength / Forelimb and hindlimb grip strength normalised against body weight	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	2.26×10^-07	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Grip Strength / Body weight	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.0257	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Coat - color - abdomen	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Hypothalamus	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Hypothalamus	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Pupil Dilation	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.0895	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Mean left eye lens density	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.214	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Potassium	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.748	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / 30kHz-evoked ABR Threshold	HOM	3f:3m	Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)	0.0315	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Phosphorus	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.817	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Hindpaw - shape	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Tremor	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Genitalia - morphology	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Viability Primary Screen / Viability Outcome	HOM	f:m	Supplied as data	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Vas Deferens	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Vas Deferens	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Head morphology	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / ST	HOM	8f:7m	Linear Model Using Generalized Least Squares framework, GLS, including Weight	0.0335	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Upper teeth appearance	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Indirect Calorimetry / Respiratory Exchange Ratio	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.0222	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Indirect Calorimetry / Carbon dioxide production	HOM	672f:588m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Ileum	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Intraperitoneal glucose tolerance test (IPGTT) / Body Weight	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Center distance travelled	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.227	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Eye	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Eye	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / 18kHz-evoked ABR Threshold	HOM	4f:3m	Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)	0.0301	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Corneal vascularization	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Chest bone	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Chest bone	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / Mean SR amplitude	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Retinal Blood Vessels Pattern	HOM	8f:6m	Fisher Exact Test framework	0.539	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Triglycerides	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.738	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Thyroid gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Thyroid gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Clavicle	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Right total retinal thickness	HOM	7f:5m	Linear Mixed Model framework, LME, not including Weight	0.00362	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Body Weight / Body weight curve	HOM	136f:109m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / Body weight	HOM	4f:3m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / PQ	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.0723	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Hematology / Platelet count	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.00913	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Activity (body position)	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Heart	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Heart	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Epididymis	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Epididymis	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Hindlimb digit - size	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Jejunum	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Digit integrity	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Thymus	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Thymus	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Skeletal Muscle	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Skeletal Muscle	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Hindlimb	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Hindlimb	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Cranium	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Cranium	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Min left eye lens density	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.237	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Skin texture - snout	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Total protein	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.829	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Echo / Respiration Rate	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.0350	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Pupil Position	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Hindlimbs - position	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Peripheral Nervous System	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Peripheral Nervous System	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Number of cervical vertebrae	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Latency to center entry	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.499	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Eyelid closure	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Vesicular Gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Vesicular Gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Oviduct	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Oviduct	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / pNN5(6>ms)	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Forelimbs - size	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Mammary gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Mammary gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Echo / LVIDd	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.797	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Fusion of vertebrae	HOM	5f:4m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Tibia	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Tail - morphology	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Iris transilumination	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Bone	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Bone	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Hindlimb nail - length	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Aspartate aminotransferase	HOM	8f:6m	Linear Mixed Model framework, LME, not including Weight	0.368	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / Preyer Reflex	HOM	4f:3m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Vocalization	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Touch escape	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Grip Strength / Forelimb and hindlimb grip strength measurement mean	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	3.50×10^-09	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Cecum	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Cecum	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Hematology / Hemoglobin	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.346	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Aorta	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Aorta	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Adrenal gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Adrenal gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Syndactylism	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Indirect Calorimetry / Heat production (metabolic rate)	HOM	672f:588m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Whole arena resting time	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.141	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Mean right eye lens density	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.375	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Teeth presence	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Vitreous	HOM	8f:6m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / QTc	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Lens	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Grip Strength / Forelimb grip strength normalised against body weight	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.405	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Head size	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Coat - color pattern - back	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Optic Disc	HOM	8f:6m	Fisher Exact Test framework	0.104	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Parotid gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Parotid gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Center average speed	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.728	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Narrow eye opening	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Sodium	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.00288	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Forepaw - shape	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Blood	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Blood	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Alive	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Rotarod / Latency to fall	HOM	24f:21m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Vagina	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Vagina	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)	HOM	8f:6m	Linear Model Using Generalized Least Squares framework, GLS, including Weight	0.0879	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Bone Marrow	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Bone Marrow	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Skin color - snout	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Trachea	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Trachea	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Quadriceps	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / HDL-cholesterol	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	1.93×10^-08	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Persistence of hyaloid vascular system	HOM	8f:6m	Fisher Exact Test framework	0.854	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.164	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Cerebral Cortex	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Cerebral Cortex	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.176	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Pupil Shape	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration	HOM	40f:35m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Periphery average speed	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.130	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Processes on vertebrae	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Eye	HOM	8f:6m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Maxilla/Pre-maxilla	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Transfer arousal	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Mouth morphology	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Echo / Stroke Volume	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.315	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Testis	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Testis	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Main olfactory bulb	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Main olfactory bulb	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Kidney	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Kidney	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Harderian Gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Harderian Gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Head bobbing	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Sciatic nerve	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Sciatic nerve	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Adult LacZ / Pituitary gland	HET	1f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Pituitary gland	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	X-ray / Number of ribs right	HOM	5f:4m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Max left eye lens density	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.827	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / rMSSD	HOM	8f:7m	Linear Mixed Model framework, LME, not including Weight	0.974	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Skin texture - ear	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Retina	HOM	8f:6m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Body Composition (DEXA lean/fat) / Body weight	HOM	8f:6m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Distance travelled - total	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.223	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Snout size	HOM	8f:7m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / Click-evoked ABR threshold	HOM	4f:3m	Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)	0.0301	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Electrocardiogram (ECG) / PR	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.142	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Alpha-amylase	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.804	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Eye Morphology / Synechia	HOM	8f:6m	Fisher Exact Test framework	1.00	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Iron	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	0.587	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Auditory Brain Stem Response / 24kHz-evoked ABR Threshold	HOM	3f:3m	Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)	0.0335	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Total cholesterol	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight	3.09×10^-08	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Genitalia - size	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	CCP-IMG	Adult LacZ / Gonadal fat pad	HET	2f:1m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Open Field / Periphery permanence time	HOM	8f:7m	Linear Mixed Model framework, LME, including Weight	0.239	Successful
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Combined SHIRPA and Dysmorphology / Forelimb nail - length	HOM	8f:7m			NotProcessed
Btbd9^{tm1b(EUCOMM)Wtsi}	HMGU	Clinical Chemistry / Albumin	HOM	8f:6m	Linear Mixed Model framework, LME, including Weight

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Tail - thickness

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Alanine aminotransferase

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.462

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Coat - hair distribution - back

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Bulging eye

HOM

8f:6m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Echo / LVPWd

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.0935

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Lipase

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.951

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Forelimb nail - shape

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / RR

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.384

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Skin texture - whole body

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Trunk curl

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Creatinine

HOM

7f:6m

Linear Mixed Model framework, LME, including Weight

0.0332

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Iris/Pupil

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Cartilage tissue

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Cartilage tissue

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Number of thoracic vertebrae

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Striatum

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Striatum

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Hematology / Mean cell hemoglobin concentration

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.975

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Sublingual Gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Sublingual Gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Indirect Calorimetry / Body weight before experiment

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP2

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Radius

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Corneal deposits

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Indirect Calorimetry / Total food intake

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.00532

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Fibula

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Hematology / Mean platelet volume

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.000123

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Percentage center time

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.245

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Shape of vertebrae

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / 6kHz-evoked ABR Threshold

HOM

4f:3m

Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)

0.0370

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Diaphragm

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Diaphragm

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Brachydactyly

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Body Composition (DEXA lean/fat) / Body length

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

2.60×10^-05

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Peyers Patch

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Peyers Patch

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Vibrissae - presence

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Small Intestine

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Small Intestine

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Lower teeth appearance

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Scapulae

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Lens Opacity

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Skin texture - back paws

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Number of Rears

HOM

32f:28m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Forelimbs - shape

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Parathyroid gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Parathyroid gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Retinal Structure

HOM

8f:6m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Skin

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Skin

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Thalamus

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Periphery distance travelled

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.708

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Lymph Node

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Lymph Node

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Esophagus

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Esophagus

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Retina (combined)

HOM

8f:6m

Fisher Exact Test framework

0.238

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Zygomatic bone

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Pancreas

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Pancreas

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Calcium

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.375

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Echo / HR

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.197

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Percentage center movement time

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.497

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Shape of ribs

HOM

5f:4m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Tail elevation

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Contact righting

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / Number of signals

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Skin color - ear

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Hematology / Hematocrit

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.173

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Hindlimb nail - number

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Grip Strength / Forelimb and hindlimb grip strength normalised against body weight

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

2.26×10^-07

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Grip Strength / Body weight

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.0257

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Coat - color - abdomen

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1_S

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Hypothalamus

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Hypothalamus

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Pupil Dilation

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.0895

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Mean left eye lens density

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.214

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Potassium

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.748

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / 30kHz-evoked ABR Threshold

HOM

3f:3m

Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)

0.0315

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Phosphorus

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.817

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Hindpaw - shape

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Tremor

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Genitalia - morphology

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Viability Primary Screen / Viability Outcome

HOM

f:m

Supplied as data

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Vas Deferens

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Vas Deferens

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Head morphology

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / ST

HOM

8f:7m

Linear Model Using Generalized Least Squares framework, GLS, including Weight

0.0335

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Upper teeth appearance

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Indirect Calorimetry / Respiratory Exchange Ratio

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.0222

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Indirect Calorimetry / Carbon dioxide production

HOM

672f:588m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Ileum

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Intraperitoneal glucose tolerance test (IPGTT) / Body Weight

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Center distance travelled

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.227

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Eye

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Eye

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / 18kHz-evoked ABR Threshold

HOM

4f:3m

Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)

0.0301

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Corneal vascularization

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Chest bone

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Chest bone

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / Mean SR amplitude

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Retinal Blood Vessels Pattern

HOM

8f:6m

Fisher Exact Test framework

0.539

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Triglycerides

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.738

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Thyroid gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Thyroid gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Clavicle

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Right total retinal thickness

HOM

7f:5m

Linear Mixed Model framework, LME, not including Weight

0.00362

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Body Weight / Body weight curve

HOM

136f:109m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / Body weight

HOM

4f:3m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / PQ

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.0723

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Hematology / Platelet count

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.00913

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Activity (body position)

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - PP1

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Heart

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Heart

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Epididymis

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Epididymis

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Hindlimb digit - size

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Jejunum

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Digit integrity

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Thymus

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Thymus

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Skeletal Muscle

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Skeletal Muscle

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Hindlimb

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Hindlimb

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Cranium

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Cranium

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Min left eye lens density

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.237

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Skin texture - snout

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Total protein

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.829

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Echo / Respiration Rate

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.0350

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Pupil Position

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Hindlimbs - position

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Peripheral Nervous System

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Peripheral Nervous System

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Number of cervical vertebrae

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Latency to center entry

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.499

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Eyelid closure

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Vesicular Gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Vesicular Gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Oviduct

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Oviduct

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / pNN5(6>ms)

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Forelimbs - size

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Mammary gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Mammary gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Echo / LVIDd

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.797

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Fusion of vertebrae

HOM

5f:4m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Tibia

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Tail - morphology

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Iris transilumination

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Bone

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Bone

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Hindlimb nail - length

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Aspartate aminotransferase

HOM

8f:6m

Linear Mixed Model framework, LME, not including Weight

0.368

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / Preyer Reflex

HOM

4f:3m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Vocalization

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Touch escape

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Grip Strength / Forelimb and hindlimb grip strength measurement mean

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

3.50×10^-09

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Cecum

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Cecum

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Hematology / Hemoglobin

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.346

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Aorta

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Aorta

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Adrenal gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Adrenal gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Syndactylism

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Indirect Calorimetry / Heat production (metabolic rate)

HOM

672f:588m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Whole arena resting time

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.141

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Mean right eye lens density

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.375

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Teeth presence

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Vitreous

HOM

8f:6m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / QTc

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Lens

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Grip Strength / Forelimb grip strength normalised against body weight

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.405

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Head size

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Coat - color pattern - back

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Optic Disc

HOM

8f:6m

Fisher Exact Test framework

0.104

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Parotid gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Parotid gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Center average speed

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.728

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Narrow eye opening

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Sodium

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.00288

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Forepaw - shape

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Blood

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Blood

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Alive

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Rotarod / Latency to fall

HOM

24f:21m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Vagina

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Vagina

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)

HOM

8f:6m

Linear Model Using Generalized Least Squares framework, GLS, including Weight

0.0879

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Bone Marrow

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Bone Marrow

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Skin color - snout

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Trachea

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Trachea

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Quadriceps

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / HDL-cholesterol

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

1.93×10^-08

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Persistence of hyaloid vascular system

HOM

8f:6m

Fisher Exact Test framework

0.854

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.164

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Cerebral Cortex

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Cerebral Cortex

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.176

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Pupil Shape

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Intraperitoneal glucose tolerance test (IPGTT) / Blood glucose concentration

HOM

40f:35m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Periphery average speed

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.130

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Processes on vertebrae

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Eye

HOM

8f:6m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Maxilla/Pre-maxilla

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Transfer arousal

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Mouth morphology

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Echo / Stroke Volume

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.315

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Testis

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Testis

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Main olfactory bulb

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Main olfactory bulb

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Kidney

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Kidney

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Harderian Gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Harderian Gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Head bobbing

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Sciatic nerve

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Sciatic nerve

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Adult LacZ / Pituitary gland

HET

1f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Pituitary gland

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

X-ray / Number of ribs right

HOM

5f:4m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Max left eye lens density

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.827

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / rMSSD

HOM

8f:7m

Linear Mixed Model framework, LME, not including Weight

0.974

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Skin texture - ear

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Retina

HOM

8f:6m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Body Composition (DEXA lean/fat) / Body weight

HOM

8f:6m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Distance travelled - total

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.223

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Snout size

HOM

8f:7m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / Click-evoked ABR threshold

HOM

4f:3m

Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)

0.0301

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Electrocardiogram (ECG) / PR

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.142

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Alpha-amylase

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.804

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Eye Morphology / Synechia

HOM

8f:6m

Fisher Exact Test framework

1.00

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Iron

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

0.587

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Auditory Brain Stem Response / 24kHz-evoked ABR Threshold

HOM

3f:3m

Reference Range Plus Test framework; quantile = 0.95 (Tails probability = 0.025)

0.0335

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Total cholesterol

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

3.09×10^-08

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Genitalia - size

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

CCP-IMG

Adult LacZ / Gonadal fat pad

HET

2f:1m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Open Field / Periphery permanence time

HOM

8f:7m

Linear Mixed Model framework, LME, including Weight

0.239

Successful

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Combined SHIRPA and Dysmorphology / Forelimb nail - length

HOM

8f:7m

NotProcessed

Btbd9^{tm1b(EUCOMM)Wtsi}

HMGU

Clinical Chemistry / Albumin

HOM

8f:6m

Linear Mixed Model framework, LME, including Weight

My Genes

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