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Gene: Adcy3

Order

Name adenylate cyclase 3

Synonyms AC3

Status ES CellsMice
tm1aphenotype data available

Links MGI:99675    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Adcy3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Adcy3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Adcy3tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased hematocrit Adcy3tm1a(EUCOMM)Wtsi HET Male postnatal 1.15E-5
increased hematocrit Adcy3tm1a(EUCOMM)Wtsi HET Female postnatal 1.15E-5
decreased hemoglobin content Adcy3tm1a(EUCOMM)Wtsi HET Male postnatal 1.51E-5
increased hemoglobin content Adcy3tm1a(EUCOMM)Wtsi HET Female postnatal 1.51E-5
decreased erythrocyte cell number Adcy3tm1a(EUCOMM)Wtsi HET Male postnatal 3.07E-5
increased erythrocyte cell number Adcy3tm1a(EUCOMM)Wtsi HET Female postnatal 3.07E-5
decreased circulating serum albumin level Adcy3tm1a(EUCOMM)Wtsi HET Female Male postnatal 8.39E-5
increased total body fat amount Adcy3tm1a(EUCOMM)Wtsi HET Female postnatal 9.79E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Legacy Phenotype Associated Images
Dysmorphology (3)
  • Adcy3tm1a(EUCOMM)Wtsi
    HEAD, HET, Female, WTSI
  • Adcy3tm1a(EUCOMM)Wtsi
    narrow eye opening, EYE, HET, Female, WTSI
  • Adcy3tm1a(EUCOMM)Wtsi
    EYE, abnormal eye morphology, corneal opacity, eye opacity, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Adcy3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene