Gene: Acat2

Name acetyl-Coenzyme A acetyltransferase 2

Synonyms
  • Tcp-1x
  • Tcp1-rs1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:87871   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Acat2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Acat2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal body wall morphology Acat2tm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
abnormal embryo size Acat2tm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
anophthalmia Acat2tm1b(KOMP)Wtsi HOM Female embryonic day 12.5 0.0
microphthalmia Acat2tm1b(KOMP)Wtsi HOM Female embryonic day 12.5 0.0
preweaning lethality, complete penetrance Acat2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased circulating chloride level Acat2tm1b(KOMP)Wtsi HET Female postnatal 7.36E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Trigeminal V nerve 2 No (2/2)
Uterus 2 No (2/562)
Vas deferens 2 No (1/361) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    respiratory system
    digestive system
    nervous system
    set of connective tissues
    reproductive system
    adipose tissue
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 3 Image Only (3/4)
Axial skeleton 3 Image Only (3/4)
Brain 3 (5/439) (3/4)
Central nervous system ganglion 3 Image Only (3/4)
Cranium 3 Image Only (3/4)
Dorsal root ganglion 3 Image Only (3/4)
Ear 3 (3/4)
Embryo 3 (3/4)
Outer ear 3 Image Only (3/4)
Eye 3 (3/4)
Femur pre-cartilage condensation 3 Image Only (3/4)
Foot 3 (3/4)
Forearm 3 (3/4)
Forebrain 3 (3/4)
Forelimb 3 (3/4)
Fronto-nasal process 3 (3/4)
Gut 3 Image Only (3/4)
Hand 3 (3/4)
Head 3 (4/439) (3/4)
Head mesenchyme 3 Image Only (3/4)
Heart 3 (3/4)
Heart ventricle 3 Image Only (3/4)
Hindbrain 3 (5/439) (3/4)
Hindlimb 3 (3/4)
Humerus pre-cartilage condensation 3 Image Only (3/4)
Inner ear 3 Image Only (3/4)
Intestine 3 Image Only (3/4)
Liver 3 (3/4)
Lower leg 3 (3/4)
Lung 3 (3/4)
Mandibular process 3 (3/4)
Maxillary process 3 (3/4)
Mesonephros of female 3 Image Only (2/4)
Mesonephros of male 3 Image Only (3/4)
Metanephros 3 Image Only (3/4)
Midbrain 3 (3/4)
Nasal septum 3 Image Only (3/4)
Nose 3 Image Only (3/4)
Notochord 3 Image Only (3/4)
Oral cavity 3 (3/4)
Outflow tract 3 Image Only (3/4)
Pancreas 3 Image Only (3/4)
Pericardium 3 Image Only (3/4)
Pharynx 3 Image Only (3/4)
Radius-ulna pre-cartilage condensation 3 Image Only (3/4)
Rib pre-cartilage condensation 3 Image Only (3/4)
Skeleton 3 Image Only (3/4)
Skin 3 (3/4)
Spinal cord 3 Image Only (3/4)
Stomach 3 Image Only (3/4)
Tail 3 (3/4)
Tail somite 3 (3/4)
Thoracic vertebral cartilage condensation 3 Image Only (3/4)
Tongue 3 Image Only (3/4)
Trachea 3 Image Only (3/4)
Trunk mesenchyme 3 Image Only (3/4)
Umbilical artery embryonic part 3 Image Only (3/4)
Umbilical vein embryonic part 3 Image Only (3/4)
Upper arm 3 (3/4)
Upper leg 3 (3/4)
Urinary system 3 Image Only (3/4)
Vibrissa 3 Image Only (3/4)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    6 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • Adult LacZ: LacZ Images Wholemount
    12 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Acat2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Acat2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Acat2tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)
Vector
Gene