Gene: 4932438A13Rik

Name RIKEN cDNA 4932438A13 gene

Synonyms
  • Tweek
  • FSA

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2444631   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for 4932438A13Rik

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all 4932438A13Rik data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size 4932438A13Riktm1b(EUCOMM)Hmgu HOM Female embryonic day 12.5 0.0
embryonic growth retardation 4932438A13Riktm1b(EUCOMM)Hmgu HOM Female embryonic day 12.5 0.0
hemorrhage 4932438A13Riktm1b(EUCOMM)Hmgu HOM Female Male embryonic day 15.5 0.0
pallor 4932438A13Riktm1b(EUCOMM)Hmgu HOM Female embryonic day 12.5 0.0
preweaning lethality, complete penetrance 4932438A13Riktm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased mean corpuscular hemoglobin concentration 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 9.19E-9
abnormal lens morphology 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 4.12E-8
cataract 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 7.34E-8
decreased mean corpuscular volume 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 3.34E-7
increased circulating chloride level 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 8.3E-7
abnormal behavior 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 1.27E-6
decreased circulating triglyceride level 4932438A13Riktm1b(EUCOMM)Hmgu HET Female Male postnatal 5.54E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354) (1/2)
Aorta 2 No (2/530) (1/2)
Bone marrow 2 No
Brain 2 No (8/530) (2/2)
Brainstem 2 No (5/530) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530) (2/2)
Cerebellum 2 No (6/530) (2/2)
Cerebral cortex 2 No (6/530) (2/2)
Epididymis 2 No (1/103) (1/2)
Esophagus 2 No (1/354) (2/2)
Eye 2 No (1/530) (2/2)
Heart 2 No (4/530) (2/2)
Hippocampus 2 No (7/530) (2/2)
Hypothalamus 2 No (5/529) (2/2)
Kidney 2 No (13/530) (2/2)
Large intestine 2 No (7/530) (2/2)
Liver 2 No (1/2)
Lower urinary tract 2 No (3/530)
Lung 2 No (4/530) (2/2)
Lymph node 2 No (2/530)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (3/354) (2/2)
Ovary 2 No (1/530) (1/2)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530) (2/2)
Peripheral nervous system 2 No (4/530) (2/2)
Peyer's patch 2 No (1/354)
Pituitary gland 2 No (2/530) (2/2)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530) (2/2)
Spinal cord 2 No (5/530) (2/2)
Spleen 2 No (3/530) (2/2)
Stomach 2 No (5/530) (2/2)
Striatum 2 No (6/530) (2/2)
Submandibular gland 2 No (2/2)
Testis 2 No (7/530) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (1/530) (2/2)
Thyroid gland 2 No (11/530)
Trachea 2 No (5/530) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/530) (1/2)
Vascular system 2 No (1/354) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system
    endocrine system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (5/413) (1/2)
Dorsal root ganglion 1 No Data Image Only
Ear 1
Embryo 1 (1/2)
Eye 1 (1/2)
Foot 1 (1/2)
Forebrain 1 (1/2)
Forelimb 1 (1/2)
Fronto-nasal process 1 Image Only
Hand 1 (1/2)
Head 1 (4/413) (1/2)
Heart 1 (1/2)
Hindbrain 1 (5/413) (1/2)
Hindlimb 1 (1/2)
Liver 1
Lung 1 Image Only
Mandibular process 1 (1/2)
Maxillary process 1
Midbrain 1 (1/2)
Nose 1 No Data (1/2)
Oral cavity 1 Image Only
Skin 1 (1/2)
Spinal cord 1 No Data (1/2)
Tail 1 (1/2)
Tail somite 1 Image Only


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Lateral Orientation
    7 Images
  • Gross Morphology Embryo E14.5-E15.5
    3 Images
  • Gross Morphology Embryo E12.5
    4 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
4932438A13Riktm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
4932438A13Riktm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene