Gene: Abca7

Name ATP-binding cassette, sub-family A (ABC1), member 7

Synonyms Abc51

Status ES CellsMice
tm2b
Mice
tm2a
phenotype data available

Links MGI:1351646   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Abca7

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Abca7 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
cardiovascular system phenotype Abca7tm2b(EUCOMM)Hmgu HOM Female Male postnatal 1.84E-8
increased heart rate variability Abca7tm2b(EUCOMM)Hmgu HOM Female Male postnatal 3.36E-7
decreased circulating glucose level Abca7tm2b(EUCOMM)Hmgu HOM Female Male postnatal 6.34E-6
increased fasted circulating glucose level Abca7tm2b(EUCOMM)Hmgu HOM Female postnatal 1.74E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    cardiovascular system
    reproductive system
    immune system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440)
Dorsal root ganglion 2 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440)
Eye 2 (1/440)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Fronto-nasal process 2 (1/4)
Hand 2
Head 2 (5/440)
Heart 2 (1/440)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Nose 2 (1/5)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Spinal cord 2 (1/4)
Tail 2 (1/440)
Tail somite 2 (1/440)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    8 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    8 Images
  • X-ray: XRay Images Dorso Ventral
    8 Images
  • X-ray: XRay Images Forepaw
    8 Images
  • Sleep Wake: Wake state (bmp file)
    14 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Abca7tm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Abca7tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene