Gene: Aire

Name autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)

Status ES CellsMice
phenotype data available

Links MGI:1338803   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Aire

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Aire data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal eye morphology Airetm1.1(NCOM)Mfgc HOM Female Male postnatal 0.0
abnormal retina morphology Airetm1.1(NCOM)Mfgc HOM Male postnatal 2.67E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (5/439) Image Only
Ear 3 Image Only
Embryo 3
Eye 3 Image Only
Foot 3 Image Only
Forebrain 3 Image Only
Forelimb 3 Image Only
Hand 3 Image Only
Head 3 (4/439) Image Only
Heart 3 Image Only
Hindbrain 3 (5/439) Image Only
Hindlimb 3 Image Only
Liver 3 Image Only
Lung 3 Image Only
Mandibular process 3 Image Only
Maxillary process 3 Image Only
Midbrain 3 Image Only
Oral cavity 3 Image Only
Skin 3 Image Only
Tail 3 Image Only
Tail somite 3 Image Only

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    17 Images
  • X-ray: XRay Images Skull Lateral Orientation
    17 Images
  • Gross Pathology and Tissue Collection
    16 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Airetm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)
Airetm1.1(NCOM)Mfgc Reporter-tagged deletion allele (post Cre, with no selection cassette)
Airetm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)