Gene: Itgae

Name integrin alpha E, epithelial-associated

Synonyms
  • alpha-E1
  • CD103

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1298377   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Itgae

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Itgae data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased neutrophil cell number Itgaetm1b(EUCOMM)Wtsi HOM Male postnatal 1.15E-8
decreased leukocyte cell number Itgaetm1b(EUCOMM)Wtsi HOM Male postnatal 2.4E-5
decreased large unstained cell number Itgaetm1b(EUCOMM)Wtsi HOM Male postnatal 9.97E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354)
Aorta 2 No (2/530)
Bone 2 No (1/515)
Brain 2 No (8/530)
Brainstem 2 No (5/530)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530)
Cerebellum 2 No (6/530)
Cerebral cortex 2 No (6/530)
Esophagus 2 No (1/354)
Eye 2 No (1/530)
Gall bladder 2 No
Heart 2 No (4/530)
Hippocampus 2 No (7/530)
Hypothalamus 2 No (5/529)
Kidney 2 No (13/530)
Large intestine 2 No (7/530)
Liver 2 No
Lower urinary tract 2 No (3/530) (2/2)
Lung 2 No (4/530)
Lymph node 2 No (2/530) (2/2)
Mammary gland 2 No
Olfactory lobe 2 No (3/354)
Oral epithelium 2 No
Ovary 2 No (1/530)
Oviduct 2 No (1/530)
Pancreas 2 No (2/530)
Parathyroid gland 2 No (2/516)
Peripheral nervous system 2 No (4/530)
Peyer's patch 2 No (1/354)
Pituitary gland 2 No (2/530)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530)
Spinal cord 2 No (5/530)
Spleen 2 No (3/530)
Stomach 2 No (5/530) (1/2)
Striatum 2 No (6/530)
Testis 2 No (7/530) (1/2)
Thymus 2 No (1/530)
Thyroid gland 2 No (11/530)
Trachea 2 No (5/530)
Uterus 2 No (1/530)
Vascular system 2 No (1/354)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system reproductive system immune system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Echo: M-Mode Images
    32 Images
  • Adult LacZ: LacZ Images Wholemount
    5 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Itgaetm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Itgaetm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Itgaetm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Itgaetm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene