Gene: Crybg1

Order

Name crystallin beta-gamma domain containing 1

Synonyms Aim1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:109544    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Crybg1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Crybg1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal eye morphology Crybg1tm1b(KOMP)Wtsi HET Female postnatal 0.0
abnormal forebrain development Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal hindbrain development Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal midbrain development Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal neural tube closure Crybg1tm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Crybg1tm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Crybg1tm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Crybg1tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased prepulse inhibition Crybg1tm1b(KOMP)Wtsi HET Female Male postnatal 3.18E-13
hypoactivity Crybg1tm1b(KOMP)Wtsi HET Female Male postnatal 3.55E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 16 (6/440) Image Only
Ear 16 (1/440) Image Only
Embryo 16 (1/440) Image Only
Eye 16 (1/440) Image Only
Foot 16 Image Only
Forebrain 16 (1/440) Image Only
Forelimb 16 (1/440) Image Only
Hand 16 Image Only
Head 16 (5/440) Image Only
Heart 16 (1/440) Image Only
Hindbrain 16 (5/440) Image Only
Hindlimb 16 (1/440) Image Only
Liver 16 (1/440) Image Only
Lung 16 (1/440) Image Only
Mandibular process 16 (1/440) Image Only
Maxillary process 16 (1/440) Image Only
Midbrain 16 (1/440) Image Only
Oral cavity 16 (1/440) Image Only
Skin 16 (1/440) Image Only
Tail 16 (1/440) Image Only
Tail somite 16 (1/440) Image Only


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    64 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Gross Pathology and Tissue Collection
    9 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Crybg1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Crybg1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene