Gene: Abca4

Name ATP-binding cassette, sub-family A (ABC1), member 4

Synonyms
  • RmP
  • D430003I15Rik
  • Rim protein
  • Abc10

Status ES CellsMice
tm1a
phenotype data available

Links MGI:109424   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Abca4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Abca4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased mean corpuscular hemoglobin Abca4tm1a(EUCOMM)Wtsi HET Female Male postnatal 4.26E-7
decreased CD4-positive, alpha beta T cell number Abca4tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.56E-5
vertebral fusion Abca4tm1a(EUCOMM)Wtsi HOM Female postnatal 1.7E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (5/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
reproductive system (2)
  • Abca4tm1a(EUCOMM)Wtsi
    OVARY, HET, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
trunk (2)
  • Abca4tm1a(EUCOMM)Wtsi
    OVARY, HET, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    41 Images
  • X-ray: XRay Images Lateral Orientation
    27 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
Legacy Phenotype Associated Images
Xray (152)
  • Abca4tm1a(EUCOMM)Wtsi
    TRUNK, HET, Male, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    HEAD, HET, Male, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    HEAD, HET, Male, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    LOWER ARM, HET, Male, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    TRUNK, HET, Female, WTSI

show all 152 images

Skin Histopathology (4)
  • Abca4tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
Eye Morphology (3)
  • Abca4tm1a(EUCOMM)Wtsi
    eyelids fail to open, RIGHT EYE, HOM, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    corneal opacity, HOM, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    persistence of hyaloid vascular system, HOM, Female, WTSI
Tail Epidermis Wholemount (2)
  • Abca4tm1a(EUCOMM)Wtsi
    abnormal epidermal pigmentation, HOM, Female, WTSI
  • Abca4tm1a(EUCOMM)Wtsi
    abnormal epidermal pigmentation, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Abca4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Abca4tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)
Vector
Gene