Previous IMPC Data Release 6.1 Notes

You are viewing a previous release. Click here for the latest release notes.

IMPC

  • Release: 6.1
  • Published: 03 December 2017

Statistical Package

  • PhenStat
  • Version: 2.14.0

Genome Assembly

  • Mus musculus
  • Version: GRCm38

Summary

  • Number of phenotyped genes: 4,364
  • Number of phenotyped mutant lines: 4,745
  • Number of phenotype calls: 52,656

Data access

Highlights

Data release 6.1

Release notes: Represents a minor release. Changes include:
  • New data from the 3i project
  • A fix to strain nomenclature for some legacy lines

Data Reports

Lines and Specimens

Phenotyping Center Mutant Lines Baseline Mice Mutant Mice
JAX 920 5,742 24,912
TCP 443 5,891 19,740
HMGU 227 2,264 4,156
KMPC 24 408 510
MARC 235 1,880 3,776
MRC Harwell 449 4,341 11,359
RBRC 71 1,674 1,509
ICS 170 1,861 2,682
WTSI 1,024 3,386 16,829
BCM 403 1,207 12,839
UC Davis 779 2,651 18,163

Experimental Data and Quality Checks

Data Type QC passed QC failed issues
categorical 11,129,868 3,389 * 14,775 *
unidimensional 8,150,815 24,321 * 188,283 *
time series 12,002,305 2,393 * 0
text 143,004 11,431 * 34,141 *
image record 315,223 0 0

* Excluded from statistical analysis.

Procedures

Select all Deselect all

Allele Types

Mutation Name Mutant Lines
Targeted Mutation a 1156
Targeted Mutation 1 1113
Targeted Mutation b 2235
Targeted Mutation 2 6
Targeted Mutation c 2
Targeted Mutation d 2
Targeted Mutation e 76

Mouse knockout programs: RRG305,FLP1,mirKO,EUCJ0019c12,IST12471H5,EUCJ0004f10,W096D02,EUCJ0079d10,YHD437,RRR454,Thy1-MAPT*P301S,pT1Betageo,RRH308,KOMP,CB0226,M076C04,EUC0047a08,NCC,EUC0050e03,EUC0027g03,XG716,EUCE0233a03,IMPC,RRJ142,EUCOMM,NCOM,YTC001,XG510,EUC0054a05

Distribution of Phenotype Annotations

More charts and status information are available from iMits.

Phenotype Associations

Select all Deselect all

Phenotype Associations Overview

We provide a 'phenome' overview of statistically significant calls. By following the links below, you'll access the details of the phenotype calls for each center.

Phenotyping Center Significant MP Calls Pipeline
JAXBrowseIMPC_001
JAXBrowseJAX_001
TCPBrowseTCP_001
HMGUBrowseIMPC_001
HMGUBrowseHMGU_001
KMPCBrowseIMPC_001
MARCBrowseIMPC_001
MRC HarwellBrowseHRWL_001
ICSBrowseICS_001
WTSIBrowseMGP_001
BCMBrowseIMPC_001
BCMBrowseBCM_001
UC DavisBrowseUCD_001

Statistical Analysis

Statistical Methods

Data Statistical Method
categorical Fisher's exact test
unidimensional Wilcoxon rank sum test with continuity correction
unidimensional Mixed Model framework, generalized least squares, equation withoutWeight
unidimensional Mixed Model framework, linear mixed-effects model, equation withoutWeight

P-value distributions

Trends

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter