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Phenotype: decreased marginal zone precursor B cell number

Definition
reduction in the number of CD23-positive, CD21-positive B cells in the marginal zone of lymphoid tissues
Synonyms
reduced marginal zone precursor B cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased marginal zone precursor B cell number

Total number of significant genotype-phenotype associations: 1

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi 		HOM   Early adult decreased marginal zone precursor B cell number Marginal zone precursor B cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

0.27% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased marginal zone precursor B cell number (1/370)

0.00% females (0/1) 0.00% males (0/1)



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