IMPC Gene variants with increased mature NK cell number
Total number of significant genotype-phenotype associations: 8
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased mature NK cell number | Mature NK cells - % of NK cellls Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | increased mature NK cell number | Mature NK cells - % of NK cellls Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased Ly6C-positive mature NK cell number | NK Subsets (Q4) Immunophenotyping |
ICS IMPC |
2.61×10-06 | |
Cluh Cluhem1(IMPC)Ccpcz |
HET | Early adult | increased Ly6C-positive mature NK cell number | NK Subsets (Q4) Immunophenotyping |
CCP-IMG IMPC |
1.14×10-05 | |
Asb2 Asb2tm2b(KOMP)Wtsi |
HET | Early adult | increased Ly6C-positive mature NK cell number | NK Subsets (Q4) Immunophenotyping |
KMPC IMPC |
2.36×10-05 | |
Spink6 Spink6em1(IMPC)Ccpcz |
HOM | Early adult | increased Ly6C-positive mature NK cell number | NK Subsets (Q2) Immunophenotyping |
CCP-IMG IMPC |
6.34×10-05 |