Phenotype: increased mature NK cell number

Definition
increase in the number of NK cells expressing the maturation marker CD11b
Synonyms
increased mature natural killer cell number
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased mature NK cell number

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM   Early adult increased mature NK cell number Mature NK cells - % of NK cellls
Spleen Immunophenotyping
WTSI
3i
0.00
Pclaf
Pclaftm1a(EUCOMM)Wtsi
HOM   Early adult increased mature NK cell number Mature NK cells - % of NK cellls
Spleen Immunophenotyping
WTSI
3i
0.00
Tmprss6
Tmprss6tm1b(EUCOMM)Wtsi
HOM Early adult increased Ly6C-positive mature NK cell number NK Subsets (Q4)
Immunophenotyping
ICS
IMPC
2.61×10-06
Cluh
Cluhem1(IMPC)Ccpcz
HET Early adult increased Ly6C-positive mature NK cell number NK Subsets (Q4)
Immunophenotyping
CCP-IMG
IMPC
1.14×10-05
Asb2
Asb2tm2b(KOMP)Wtsi
HET Early adult increased Ly6C-positive mature NK cell number NK Subsets (Q4)
Immunophenotyping
KMPC
IMPC
2.36×10-05
Spink6
Spink6em1(IMPC)Ccpcz
HOM Early adult increased Ly6C-positive mature NK cell number NK Subsets (Q2)
Immunophenotyping
CCP-IMG
IMPC
6.34×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.42% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased mature NK cell number (6/422)

4.05% females (3/74) 4.05% males (3/74)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter