Phenotype: decreased Ly6C-positive immature NK cell number

Definition
reduction in the number of immature NK cells expressing the memory marker Ly6C
Synonyms
reduced Ly6C-positive immature NK cell number,  decreased Ly6C-positive immature natural killer cell number
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased Ly6C-positive immature NK cell number

Total number of significant genotype-phenotype associations: 7

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM   Early adult decreased Ly6C-positive immature NK cell number Ly6C+ immature NK cells - % of lymphocytes
Spleen Immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM   Early adult decreased Ly6C-positive immature NK cell number Ly6C+ immature NK cells - % of lymphocytes
Spleen Immunophenotyping
WTSI
3i
0.00
Asb2
Asb2tm2b(KOMP)Wtsi
HET Early adult decreased Ly6C-positive immature NK cell number NK Subsets (Q3)
Immunophenotyping
KMPC
IMPC
1.40×10-11
Bach2
Bach2tm1b(EUCOMM)Wtsi
HOM Early adult decreased Ly6C-positive immature NK cell number NK Subsets (Q1)
Immunophenotyping
HMGU
IMPC
1.13×10-06
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM   Early adult decreased Ly6C-positive immature NK cell number NK Subsets (Q1)
Immunophenotyping
HMGU
IMPC
8.60×10-06
Spink6
Spink6em1(IMPC)Ccpcz
HOM   Early adult decreased Ly6C-positive immature NK cell number NK Subsets (Q3)
Immunophenotyping
CCP-IMG
IMPC
3.14×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.42% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased Ly6C-positive immature NK cell number (6/422)

2.82% females (2/71) 1.41% males (1/71)

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