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Phenotype: increased CD103-positive CD11b-low dendritic cell number

Definition
increase in the number of CD11b-low dendritic cells expressing CD103, a marker of tissue residency
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased CD103-positive CD11b-low dendritic cell number

Total number of significant genotype-phenotype associations: 3

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi 		HOM   Early adult increased CD103-positive CD11b-low dendritic cell number CD103+ CD11b-low cDC - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased CD103-positive CD11b-low dendritic cell number CD103+ CD11b-low cDC - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased CD103-positive CD11b-low dendritic cell number CD103+ CD11b-low cDC - % of CD11b-low cDC
Spleen Immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

0.68% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased CD103-positive CD11b-low dendritic cell number (3/444)

0.00% females (0/3) 0.00% males (0/3)

Select a parameter    



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