Phenotype: increased memory-marker CD4-positive NK T cell number

Definition
increase in the number of memory-marker CD4-positive NK T cells with a CD44+ CD62L- phenotype
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased memory-marker CD4-positive NK T cell number

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM   Early adult increased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Spred1
Spred1em1(IMPC)Ccpcz
HOM Early adult increased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.85×10-12
Psmb11
Psmb11em1(IMPC)Ccpcz
HOM Early adult increased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.16×10-06
Pax5
Pax5tm1b(EUCOMM)Wtsi
HET Early adult increased memory-marker CD4-positive NK T cell number CD4 CD44+CD62L- NKT cells
Immunophenotyping
HMGU
IMPC
4.63×10-06
Tppp3
Tppp3em1(IMPC)Ccpcz
HET Early adult increased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
3.05×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.64% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased memory-marker CD4-positive NK T cell number (5/778)

1.25% females (4/320) 0.32% males (1/317)

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