IMPC Gene variants with decreased CD4-negative NK T cell number
Total number of significant genotype-phenotype associations: 15
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Effector CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD4- NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Gimap6 Gimap6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Effector CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Gimap6 Gimap6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD4-negative NK T cell number | Total CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Hbs1l Hbs1ltm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD4- NKT cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD4- NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
HMGU IMPC |
2.44×10-09 | |
Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | DN CD44+CD62L- NKT cells Immunophenotyping |
CCP-IMG IMPC |
3.94×10-06 | |
Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
CCP-IMG IMPC |
6.14×10-06 | |
Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
CCP-IMG IMPC |
6.17×10-06 | |
Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | DN CD44+CD62L- NKT cells Immunophenotyping |
CCP-IMG IMPC |
1.22×10-05 | |
Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | DN CD44+CD62L- NKT cells Immunophenotyping |
HMGU IMPC |
2.16×10-05 | |
Ube3c Ube3ctm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
HMGU IMPC |
9.11×10-05 |