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Phenotype: increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number

Definition
increase in the number of the CD4+, CD25+ alpha-beta regulatory T cells with a CD44+ CD62L- memory phenotype
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number

Total number of significant genotype-phenotype associations: 9

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Effector Treg cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Resting Treg cells - % of Treg
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Resting Treg cells - % of Treg
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cttnbp2
Cttnbp2tm1b(KOMP)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Effector Treg cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Dph6
Dph6tm1a(KOMP)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Effector Treg cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Gmds
Gmdstm1a(KOMP)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Resting Treg cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Hbs1l
Hbs1ltm1a(KOMP)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Effector Treg cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Pclaf
Pclaftm1a(EUCOMM)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Resting Treg cells - % of Treg
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Pepd
Pepdtm1a(KOMP)Wtsi 		HOM   Early adult increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Effector Treg cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

1.95% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number (9/462)

0.00% females (0/9) 0.00% males (0/9)

Select a parameter    



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