Phenotype: decreased fasted circulating glucose level

Phenotype associations stats

1.88% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased fasted circulating glucose level (76/4032)

1.15% females (46/3983) 1.77% males (71/4007)

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Gene variants with decreased fasted circulating glucose level

Total number of significant genotype-phenotype associations: 117

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Cdh23
Cdh23tm2b(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 2.64E-15
Sptssb
Sptssbtm1b(KOMP)Mbp
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 7.25E-15
Cxcl9
Cxcl9tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 2.77E-13
Gnao1
Gnao1tm1b(EUCOMM)Hmgu
HET Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 5.15E-13
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 1.26E-11
Jup
Juptm1.1(KOMP)Vlcg
HET Female postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 1.67E-10
Dcun1d3
Dcun1d3em1(IMPC)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 1.81E-10
Rexo2
Rexo2tm1b(EUCOMM)Wtsi
HET Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 8.93E-10
Spock1
Spock1em1(IMPC)H
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 1.09E-9
Kcnj11
Kcnj11tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 6.7E-9
Slc24a5
Slc24a5tm1b(KOMP)Mbp
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 2.29E-8
Cand1
Cand1em1(IMPC)Mbp
HET Female postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 2.48E-8
Ndrg1
Ndrg1tm2b(KOMP)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 3.25E-8
Prkaa2
Prkaa2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 5.26E-8
Adra2a
Adra2atm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 6.03E-8
Bhlhe40
Bhlhe40tm1b(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 7.06E-8
Vti1a
Vti1atm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 1.22E-7
Dynlrb2
Dynlrb2tm1a(KOMP)Wtsi
HET Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 1.92E-7
Masp1
Masp1tm1.1(KOMP)Vlcg
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 3.28E-7
Il18rap
Il18raptm1b(KOMP)Wtsi
HOM Female postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration ICS | IMPC 3.6E-7
Vegfb
Vegfbtm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 3.87E-7
Tmtc4
Tmtc4tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 4.14E-7
Mars2
Mars2tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 4.6E-7
Atrip
Atriptm1b(KOMP)Wtsi
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 6.15E-7
Gh
Ghtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 7.43E-7
Snx22
Snx22tm1.1(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 7.59E-7
Eml1
Eml1em1(IMPC)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 9.16E-7
Spata7
Spata7tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 1.86E-6
Arid1b
Arid1bem1(IMPC)Tcp
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 3.98E-6
Akr1d1
Akr1d1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 5.51E-6
Alg2
Alg2tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 5.86E-6
Mkrn3
Mkrn3em1(IMPC)Tcp
HOM Female postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 7.65E-6
Trim55
Trim55tm2b(EUCOMM)Hmgu
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 8.5E-6
Slc20a2
Slc20a2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 8.66E-6
Mep1a
Mep1atm1a(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 8.93E-6
4930563E22Rik
4930563E22Riktm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 9.67E-6
Ncoa1
Ncoa1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 9.73E-6
Cpgi5563
Cpgi5563tm1.1(NCC)WCS
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 1.06E-5
Calhm1
Calhm1tm1.1(KOMP)Vlcg
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 1.11E-5
Haao
Haaotm2b(KOMP)Mbp
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 1.16E-5
Cabp1
Cabp1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 1.24E-5
Rnf183
Rnf183tm1b(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 1.29E-5
Gramd1c
Gramd1ctm1b(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 1.32E-5
Tmem260
Tmem260tm1a(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 1.39E-5
Fam160a2
Fam160a2em1(IMPC)Tcp
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 1.4E-5
Cldn13
Cldn13tm1.1(KOMP)Vlcg
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 1.43E-5
Slc43a3
Slc43a3tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 1.54E-5
Avp
Avptm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 1.72E-5
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 1.72E-5
Rcc2
Rcc2tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 1.88E-5
Colca2
Colca2tm1b(NCOM)Mfgc
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 2.0E-5
Prag1
Prag1em2(IMPC)Tcp
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 2.09E-5
Elmo1
Elmo1tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 2.66E-5
D1Ertd622e
D1Ertd622etm1.1(KOMP)Vlcg
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 2.74E-5
Pkd2l2
Pkd2l2tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 2.91E-5
Map3k1
Map3k1tm1a(KOMP)Wtsi
HET Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 2.96E-5
Isca1
Isca1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 3.4E-5
Nsd3
Nsd3tm1b(EUCOMM)Hmgu
HET Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 4.0E-5
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 4.94E-5
Irx3
Irx3em2(IMPC)H
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 5.28E-5
Mpz
Mpzem1(IMPC)Tcp
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 5.4E-5
Tcerg1l
Tcerg1ltm1a(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 5.57E-5
H13
H13tm1b(KOMP)Wtsi
HET Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 5.68E-5
Folr1
Folr1tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 6.06E-5
Cand2
Cand2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 6.07E-5
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration UC Davis | IMPC 6.15E-5
Ppm1a
Ppm1atm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 6.17E-5
Plac9a
Plac9atm1b(EUCOMM)Hmgu
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 6.26E-5
Prss2
Prss2tm1.1(KOMP)Vlcg
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 6.43E-5
Irf8
Irf8tm1b(KOMP)Wtsi
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 7.86E-5
Tmem79
Tmem79tm1.1(KOMP)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration JAX | IMPC 8.03E-5
Ddx55
Ddx55tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 8.32E-5
Tulp3
Tulp3tm1b(EUCOMM)Hmgu
HET Female postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration MRC Harwell | IMPC 8.67E-5
Usp15
Usp15tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration WTSI | IMPC 8.95E-5
Tenm4
Tenm4em1(IMPC)Tcp
HOM Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 9.57E-5
Baz2a
Baz2aem1(IMPC)Tcp
HOM Female Male postnatal decreased fasted circulating glucose level Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration TCP | IMPC 9.57E-5

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