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Phenotype: increased KLRG1+ CD8 alpha-beta T cell number

Definition
increase in the number of CD8+ alpha beta T cells that express KLRG1, a marker of effector and memory T cells
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased KLRG1+ CD8 alpha-beta T cell number

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Bach2
Bach2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi 		HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD8+
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping
Whole blood peripheral blood leukocyte immunophenotyping

 Phenotype associations stats

0.84% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased KLRG1+ CD8 alpha-beta T cell number (4/474)

20.00% females (1/5) 20.00% males (1/5)

Select a parameter    



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