MP:0013026 (decreased Ly6C low monocyte number) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: decreased Ly6C low monocyte number

Definition

decrease in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 3

Gene / Allele	Zygosity	Sex	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi}	HOM		Early adult	decreased Ly6C low monocyte number	Ly6Clow monocyte percentage Whole blood peripheral blood leukocyte immunophenotyping	WTSI 3i	0.00
Pycr2 Pycr2^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	decreased Ly6C low monocyte number	Ly6Clow monocyte number Whole blood peripheral blood leukocyte immunophenotyping	WTSI 3i	0.00

Download data as: TSV XLS

Procedure
Whole blood peripheral blood leukocyte immunophenotyping

0.44% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased Ly6C low monocyte number (2/450)

11.11% females (1/9) 33.33% males (2/6)

Select a parameter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox