Phenotype: increased Ly6C high monocyte number

Definition
increase in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased Ly6C high monocyte number

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM Early adult increased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Early adult increased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Early adult increased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM Early adult increased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Herc1
Herc1em3(IMPC)Wtsi
HOM Early adult increased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Trappc9
Trappc9tm1a(EUCOMM)Wtsi
HOM Early adult increased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased Ly6C high monocyte number (6/450)

85.71% females (6/7) 0.00% males (0/1)



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