Phenotype: increased KLRG1-positive NK cell number

Definition
increase in the number of KLRG1 positive NK cells that represent a maturation subset of NK cells and is linked to NK cell proliferation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased KLRG1-positive NK cell number

Total number of significant genotype-phenotype associations: 13

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1-positive NK cell number KLRG1+ NK cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1-positive NK cell number KLRG1+ NK cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1-positive NK cell number KLRG1+ mature NK cell percentage
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1-positive NK cell number KLRG1+ NK cells - % of NK cells
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Fbxw26
Fbxw26tm1b(KOMP)Wtsi
HOM   Early adult increased KLRG1-positive NK cell number KLRG1+ NK cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Ncf2
Ncf2tm1a(EUCOMM)Wtsi
HOM Early adult increased KLRG1-positive NK cell number KLRG1+ mature NK cell percentage
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00
Tmem127
Tmem127tm1(KOMP)Wtsi
HOM Early adult increased KLRG1-positive NK cell number KLRG1+ mature NK cell percentage
Whole blood peripheral blood leukocyte immunophenotyping
WTSI
3i
0.00

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.48% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased KLRG1-positive NK cell number (7/474)

26.67% females (4/15) 23.53% males (4/17)

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