banner
Genes Phenotypes Help, News, Blog

Phenotype: decreased large unstained cell number

Definition
decreased number of larger than normal cells which are unstained using routine blood count methodologies; large unstained cells (LUC) are larger than normal lymphocytes, and may be atypical lymphocytes, myeloperoxidase deficient cells or peroxidase negative blasts
Synonyms
decreased LUC number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased large unstained cell number

Total number of significant genotype-phenotype associations: 22

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Fabp1
Fabp1tm1b(EUCOMM)Hmgu 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 1.18×10-11
Rab19
Rab19tm1b(EUCOMM)Hmgu 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 ICS
IMPC		 1.43×10-08
Pdpr
Pdprtm1b(EUCOMM)Wtsi 		HOM   Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 ICS
IMPC		 1.69×10-07
Pkn1
Pkn1tm1b(KOMP)Wtsi 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 2.52×10-07
Dyrk1b
Dyrk1btm1b(EUCOMM)Wtsi 		HET   Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 ICS
IMPC		 7.55×10-07
Dyrk2
Dyrk2em1(IMPC)Ics 		HET Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 ICS
IMPC		 1.31×10-06
Itgae
Itgaetm1b(EUCOMM)Wtsi 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 3.30×10-06
Avp
Avptm1b(EUCOMM)Wtsi 		HET Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 7.96×10-06
Xbp1
Xbp1tm1b(EUCOMM)Wtsi 		HET Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 1.71×10-05
Ikzf3
Ikzf3tm1(KOMP)Vlcg 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 RBRC
IMPC		 3.32×10-05
Stx7
Stx7em1(IMPC)Rbrc 		HOM   Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 RBRC
IMPC		 3.99×10-05
Blnk
Blnkem1(IMPC)H 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 5.76×10-05
Elmod1
Elmod1tm1b(EUCOMM)Hmgu 		HOM   Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 MRC Harwell
IMPC		 5.93×10-05
Ptdss1
Ptdss1tm1b(EUCOMM)Hmgu 		HOM   Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 ICS
IMPC		 7.25×10-05
Ecrg4
Ecrg4tm1b(EUCOMM)Hmgu 		HOM   Early adult decreased large unstained cell number Large Unstained Cell (LUC) count
Hematology		 ICS
IMPC		 9.63×10-05
Ppm1m
Ppm1mtm2b(EUCOMM)Hmgu 		HOM Early adult decreased large unstained cell number Large Unstained Cell (LUC) differential count
Hematology		 MRC Harwell
IMPC		 9.87×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Hematology

 Phenotype associations stats

1.72% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased large unstained cell number (16/931)

0.62% females (6/971) 1.03% males (10/973)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter