Phenotype: decreased cardiac stroke volume

Definition
reduction in the volume of blood pushed into the aorta with each beat of the heart
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cardiac stroke volume

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Nek1
Nek1em1(IMPC)Bay
HOM Early adult decreased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
1.45×10-06
Kcng2
Kcng2em1(IMPC)Bay
HOM Early adult decreased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
2.44×10-06
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM   Early adult decreased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
4.31×10-06
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu
HET Early adult decreased cardiac stroke volume Stroke Volume
Echo
HMGU
IMPC
5.29×10-06
Jtb
Jtbtm1b(EUCOMM)Hmgu
HET Early adult decreased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
4.07×10-05
Mgat1
Mgat1tm1b(EUCOMM)Hmgu
HET Early adult decreased cardiac stroke volume Stroke Volume
Echo
HMGU
IMPC
8.68×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cardiac stroke volume (6/1836)

0.00% females (0/1817) 0.33% males (5/1534)



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