Phenotype: increased effector memory CD8-positive, alpha-beta T cell number
Definition increased number of CD8-positive, alpha beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative
Synonyms
- increased effector CD8-positive, alpha-beta memory T lymphocyte number
- increased effector CD8-positive, alpha-beta memory T lymphocyte number
- increased effector CD8-positive, alpha-beta memory T-cell number
- increased effector CD8-positive, alpha-beta memory T-cell number
- increased effector memory CD8-positive, alpha-beta T-cell number
- increased effector memory CD8-positive, alpha-beta T-lymphocyte number
- increased effector CD8-positive, alpha-beta memory T-lymphocyte number
- increased effector CD8-positive, alpha-beta memory T cell number
- increased effector memory CD8-positive, alpha-beta T lymphocyte number
Procedure
- Immunophenotyping (IMPC, v1)
- Buffy coat peripheral blood leukocyte immunophenotyping (MGP, v1)
- FACS (ICS, v1)
- Immunophenotyping (ICS, v2)
- Immunophenotyping (TCPLA, v1)
- Immunophenotyping (UCDLA, v1)
- Immunophenotyping (HMGULA, v1)
- Immunophenotyping (RBRCLA, v1)
- Mesenteric Lymph Node Immunophenotyping (MGP, v1)
- Spleen Immunophenotyping (MGP, v1)
- Whole blood peripheral blood leukocyte immunophenotyping (SLM, v1)
- Whole blood peripheral blood leukocyte immunophenotyping (MGP, v1)
MP browserMP:0010850
Phenotype associations stats
1.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased effector memory CD8-positive, alpha-beta T cell number (22/1328)
1.23% females (16/1301) 1.16% males (15/1298)
Select a parameter
Gene variants with increased effector memory CD8-positive, alpha-beta T cell number
Total number of significant genotype-phenotype associations: 41
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Procedure | Parameter | Phenotyping Center | Source | P Value | Data |
---|---|---|---|---|---|---|---|---|
Arhgap30 Arhgap30^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell percentage | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Effector CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Hbs1l Hbs1l^{tm1a(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Effector CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Pepd Pepd^{tm1a(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sgms1 Sgms1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 5.82E-24 | ||
Fbxo7 Fbxo7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 1.93E-20 | ||
Spns2 Spns2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 1.24E-9 | ||
Hmgb1 Hmgb1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 4.3E-9 | ||
Mlec Mlec^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 1.03E-8 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell percentage | WTSI | 3i | 9.0E-7 | ||
Mpg Mpg^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell percentage | WTSI | 3i | 9.0E-7 | ||
Ccdc106 Ccdc106^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 3.6E-6 | ||
Reg3g Reg3g^{tm1a(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 5.95E-6 | ||
Arpc1b Arpc1b^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell percentage | WTSI | 3i | 2.12E-5 | ||
Naga Naga^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 4.57E-5 | ||
Dusp3 Dusp3^{tm1b(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 6.57E-5 | ||
Sytl1 Sytl1^{tm1a(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 6.8E-5 | ||
Prss53 Prss53^{em3(IMPC)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell percentage | WTSI | 3i | 7.67E-5 | ||
Arhgap25 Arhgap25^{tm1a(KOMP)Wtsi} |
HOM | postnatal | increased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 9.65E-5 |