Phenotype: increased effector memory CD4-positive, alpha-beta T cell number

Definition increased number of CD4-positive, alpha-beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative

Synonyms
  • increased effector memory CD4-positive, alpha-beta T-cell number
  • increased effector memory CD4-positive, alpha-beta T-cell number
  • increased effector memory CD4-positive, alpha-beta T lymphocyte number
  • increased effector memory CD4-positive, alpha-beta T lymphocyte number
  • increased effector memory CD4-positive, alpha-beta T-lymphocyte number
  • increased effector CD4-positive, alpha-beta memory T lymphocyte number
  • increased effector CD4-positive, alpha-beta memory T cell number
  • increased effector CD4-positive, alpha-beta memory T-lymphocyte number
  • increased effector CD4-positive, alpha-beta memory T-cell number
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MP browserMP:0010844

Phenotype associations stats

1.96% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased effector memory CD4-positive, alpha-beta T cell number (26/1328)

0.85% females (11/1296) 0.62% males (8/1292)

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Gene variants with increased effector memory CD4-positive, alpha-beta T cell number

Total number of significant genotype-phenotype associations: 35

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Arhgap30
Arhgap30tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.0
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 0.0
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.0
Atp11a
Atp11atm1a(KOMP)Wtsi
HET Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 0.0
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.0
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.0
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.0
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.0
Pepd
Pepdtm1a(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 0.0
Spns2
Spns2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 2.55E-40
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 4.74E-14
Arhgap25
Arhgap25tm1a(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 1.56E-7
Egfr
Egfrtm1a(EUCOMM)Wtsi
HET Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 4.43E-7
Bap1
Bap1tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 1.1E-6
Supt7l
Supt7ltm1a(EUCOMM)Wtsi
HET Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 1.58E-6
Tmod1
Tmod1tm1a(KOMP)Wtsi
HET Female postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 1.67E-6
Spns2
Spns2tm1a(KOMP)Wtsi
HOM Female postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 2.53E-6
Sytl1
Sytl1tm1a(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 3.68E-6
Zkscan14
Zkscan14tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 5.29E-6
Xpnpep1
Xpnpep1tm1a(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 1.57E-5
Enc1
Enc1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 2.12E-5
Etv3
Etv3em1(IMPC)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 2.12E-5
Mkrn2
Mkrn2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 2.58E-5
Hprt
HprtTg(CMV-Cre)Brd
HOM Female postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 4.24E-5
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 5.41E-5
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 6.2E-5
Arhgap18
Arhgap18tm1a(KOMP)Wtsi
HOM Female postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 8.52E-5

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