Phenotype: prolonged RR interval

Definition increase in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate

Synonyms
  • increased RR interval
  • increased RR interval
  • widened RR interval
  • widened RR interval

MP browserMP:0010506

Login to register interest

Phenotype associations stats

0.60% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged RR interval (17/2826)

0.46% females (13/2809) 0.46% males (13/2814)



Gene variants with prolonged RR interval

Total number of significant genotype-phenotype associations: 26

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Rab4a
Rab4atm1b(EUCOMM)Hmgu
HOM Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 5.15E-10
Gcsh
Gcshem1(IMPC)H
HET Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 5.35E-9
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.02E-8
Bbox1
Bbox1tm1a(KOMP)Wtsi
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 1.35E-7
Sbno1
Sbno1tm1b(EUCOMM)Hmgu
HET Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 3.05E-7
Got1
Got1tm1b(EUCOMM)Hmgu
HET Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 9.51E-7
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg
HOM Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.41E-6
Uhrf2
Uhrf2tm1b(EUCOMM)Wtsi
HOM Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 2.45E-6
Unc45a
Unc45atm1b(EUCOMM)Hmgu
HET Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 5.28E-5
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.65E-5
Vgf
Vgfem1(IMPC)H
HOM Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 6.27E-5
Stx1a
Stx1atm1b(EUCOMM)Hmgu
HOM Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 7.94E-5
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 8.07E-5
Ccl9
Ccl9tm1.1(KOMP)Vlcg
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 8.22E-5
Ccr6
Ccr6tm1.1(KOMP)Vlcg
HOM Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 8.7E-5
Rest
Resttm2b(EUCOMM)Wtsi
HET Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 9.18E-5
Fer1l4
Fer1l4tm1b(EUCOMM)Hmgu
HOM Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 9.94E-5

Download data as: TSV XLS