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Phenotype: decreased respiratory quotient

Definition
reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls
Synonyms
decreased RQ,  reduced respiratory exchange ratio,  reduced RQ,  decreased respiratory exchange ratio
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased respiratory quotient

Total number of significant genotype-phenotype associations: 41

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Lratd2
Lratd2em1(IMPC)Ccpcz 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 CCP-IMG
IMPC		 0.00
Slc24a3
Slc24a3em1(IMPC)Kmpc 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 KMPC
IMPC		 3.07×10-20
Bach2
Bach2tm1b(EUCOMM)Wtsi 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 1.69×10-16
Itgb6
Itgb6em1(IMPC)Ccpcz 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 CCP-IMG
IMPC		 2.22×10-16
Neurod2
Neurod2em1(IMPC)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 1.14×10-15
Bbs5
Bbs5tm1b(EUCOMM)Wtsi 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 MRC Harwell
IMPC		 6.78×10-12
Wsb2
Wsb2tm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 2.12×10-10
Cdkl5
Cdkl5tm1dIcs 		HEM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 ICS
IMPC		 1.15×10-09
Tent5a
Tent5aem1(IMPC)Ccpcz 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 CCP-IMG
IMPC		 1.30×10-09
Strbp
Strbpem1(IMPC)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 2.22×10-09
Bscl2
Bscl2tm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 ICS
IMPC		 7.94×10-09
Gnao1
Gnao1tm1b(EUCOMM)Hmgu 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 MRC Harwell
IMPC		 1.79×10-07
Mamld1
Mamld1tm1.1(NCOM)Mfgc 		HEM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 TCP
IMPC		 4.47×10-07
Spop
Spoptm1b(KOMP)Wtsi 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 TCP
IMPC		 7.17×10-07
Prss48
Prss48em1(IMPC)Ccpcz 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 CCP-IMG
IMPC		 8.11×10-07
Sez6l
Sez6ltm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 MRC Harwell
IMPC		 9.96×10-07
Ube3a
Ube3aem1(IMPC)Hmgu 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 1.05×10-06
Ube3a
Ube3aem1(IMPC)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 1.40×10-06
Cystm1
Cystm1tm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 2.38×10-06
Zscan21
Zscan21tm2b(EUCOMM)Wtsi 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 BCM
IMPC		 4.84×10-06
Car14
Car14tm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 4.84×10-06
Gatm
Gatmtm1b(KOMP)Wtsi 		HOM   Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 6.10×10-06
Hoxa2
Hoxa2tm1b(EUCOMM)Wtsi 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 9.68×10-06
Prkd2
Prkd2em1(IMPC)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 1.26×10-05
Phgdh
Phgdhtm1b(KOMP)Wtsi 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 KMPC
IMPC		 2.25×10-05
Gad2
Gad2tm1b(EUCOMM)Wtsi 		HOM   Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 2.36×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 RBRC
IMPC		 3.64×10-05
Klhl29
Klhl29tm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 ICS
IMPC		 3.82×10-05
Phf19
Phf19tm1.1(KOMP)Vlcg 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 UC Davis
IMPC		 4.15×10-05
Sox14
Sox14em1(IMPC)Ccpcz 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 CCP-IMG
IMPC		 4.42×10-05
Ube3c
Ube3ctm1b(EUCOMM)Hmgu 		HOM   Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 RBRC
IMPC		 4.85×10-05
Prdm14
Prdm14tm1a(EUCOMM)Wtsi 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 BCM
IMPC		 4.95×10-05
Bbip1
Bbip1em1(IMPC)Ccpcz 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 CCP-IMG
IMPC		 6.18×10-05
Adprm
Adprmtm1b(EUCOMM)Hmgu 		HOM Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 7.11×10-05
Tanc2
Tanc2em1(IMPC)Hmgu 		HOM   Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 HMGU
IMPC		 8.39×10-05
Pcx
Pcxtm1b(EUCOMM)Wtsi 		HET Early adult decreased respiratory quotient Respiratory Exchange Ratio
Indirect Calorimetry		 MRC Harwell
IMPC		 9.71×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Indirect Calorimetry

 Phenotype associations stats

1.15% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased respiratory quotient (35/3032)

1.13% females (11/970) 0.83% males (25/3004)



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