Phenotype: abnormal retinal blood vessel morphology

Phenotype associations stats

1.12% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal retinal blood vessel morphology (48/4286)

0.52% females (22/4260) 0.85% males (36/4235)

Gene variants with abnormal retinal blood vessel morphology

Total number of significant genotype-phenotype associations: 58

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Ube2a
Ube2atm1.1(KOMP)Vlcg
HEM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 0.0
Mpdz
Mpdzem1(IMPC)J
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 1.36E-18
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 3.58E-15
Mapt
Mapttm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 9.64E-14
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 2.22E-12
Timp3
Timp3tm1.1(KOMP)Vlcg
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 1.9E-9
Atxn7l3
Atxn7l3tm1.1(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 4.69E-9
Lrrc51
Lrrc51tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.78E-8
Lss
Lsstm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.99E-8
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.36E-8
Tnpo2
Tnpo2tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.88E-7
Trmt1
Trmt1tm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 2.93E-7
Cacna2d4
Cacna2d4em1(IMPC)J
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 3.12E-7
S1pr3
S1pr3tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.36E-7
Hdac1
Hdac1tm1b(EUCOMM)Wtsi
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.25E-6
Gpr25
Gpr25em1(IMPC)Bay
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.71E-6
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.25E-6
Inhbb
Inhbbtm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 4.31E-6
5330417C22Rik
5330417C22Riktm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 6.04E-6
Hnf4a
Hnf4atm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.03E-6
Rnf10
Rnf10em1(IMPC)Bay
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 8.46E-6
Etfdh
Etfdhtm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.64E-6
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 8.87E-6
Prdm5
Prdm5em1(IMPC)Tcp
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 9.7E-6
Gjc3
Gjc3em1(IMPC)Bay
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.11E-5
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.14E-5
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.5E-5
Emc8
Emc8tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 1.77E-5
Nxn
Nxnem1(IMPC)Bay
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.9E-5
Klk14
Klk14tm1.1(KOMP)Vlcg
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.14E-5
Rcn1
Rcn1tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.61E-5
Rnf38
Rnf38tm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.66E-5
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.7E-5
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.92E-5
Pcsk1
Pcsk1tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 3.07E-5
Wdsub1
Wdsub1tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.28E-5
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.53E-5
Asb2
Asb2tm2b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 3.63E-5
Cr1l
Cr1ltm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.24E-5
Thap1
Thap1em1(IMPC)J
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.24E-5
Tmem151b
Tmem151btm1b(KOMP)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 5.45E-5
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.74E-5
Pdhx
Pdhxtm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.93E-5
Nbas
Nbastm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.19E-5
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.36E-5
Foxk2
Foxk2em1(IMPC)J
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 8.65E-5
Actrt3
Actrt3tm1.1(KOMP)Vlcg
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 9.33E-5
Ndufa8
Ndufa8tm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 9.87E-5

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Images

  • Polr1etm1a(KOMP)Wtsi
    eye, abnormal retinal blood vessel structure, abnormal optic disc morphology, HET, Female, WTSI
  • Polr1etm1a(KOMP)Wtsi
    eye, abnormal optic disc morphology, abnormal retinal blood vessel structure, HET, Female, WTSI
  • Kptntm1a(EUCOMM)Wtsi
    eye, abnormal retinal blood vessel structure, HOM, Female, WTSI
  • Stard6tm1a(KOMP)Wtsi
    eye, abnormal retinal blood vessel morphology, HOM, Male, WTSI
  • Stard6tm1a(KOMP)Wtsi
    eye, abnormal retinal blood vessel morphology, HOM, Male, WTSI

Associated Images

  • Eye Morphology: Images Ophthalmoscopy
    63 Images