Phenotype: increased red blood cell distribution width

Definition higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism

Synonyms
  • high RDW
  • high RDW
  • high red blood cell distribution width
  • high red blood cell distribution width
  • increased red blood cell size variability
  • increased erythrocyte distribution width
Show more
Related
Synonyms
  • Anisocytosis
  • Anisocytosis
  • anisocytosis
  • anisocytosis

MP browserMP:0010067

Phenotype associations stats

1.76% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased red blood cell distribution width (54/3061)

1.01% females (30/2982) 1.79% males (54/3015)



Gene variants with increased red blood cell distribution width

Total number of significant genotype-phenotype associations: 86

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Irgm1
Irgm1em1(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 0.0
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 0.0
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.99E-30
Fbxo38
Fbxo38em2(IMPC)Marc
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.75E-15
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.49E-15
Herc1
Herc1em3(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.0E-14
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.83E-13
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.32E-12
Mul1
Mul1em1(IMPC)H
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 5.18E-12
Pdzd8
Pdzd8tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.37E-12
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.98E-10
Etaa1
Etaa1em1(IMPC)Marc
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.3E-9
Crlf3
Crlf3em1(IMPC)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.97E-9
Becn1
Becn1tm1b(KOMP)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.41E-9
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.53E-9
Hbb-bh2
Hbb-bh2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width RBRC | IMPC 9.13E-9
Hpf1
Hpf1em1(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.15E-8
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.28E-8
Tbc1d22a
Tbc1d22atm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.63E-8
Prkab1
Prkab1em2(IMPC)Mbp
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 5.32E-8
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.06E-7
Kat2b
Kat2bem1(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.43E-7
Galnt18
Galnt18tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.96E-7
Atp5e
Atp5etm1b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.6E-7
3830406C13Rik
3830406C13Riktm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.79E-7
Klhl42
Klhl42tm1b(EUCOMM)Hmgu
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.51E-7
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 9.61E-7
Sgsm1
Sgsm1tm1b(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.59E-6
Micu2
Micu2tm1a(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.65E-6
Rreb1
Rreb1tm1b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.75E-6
Sdc4
Sdc4tm2b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.9E-6
Lpin2
Lpin2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 5.44E-6
Fbxo11
Fbxo11tm2b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 5.49E-6
Ninj2
Ninj2tm1a(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.7E-6
Angptl4
Angptl4tm1b(EUCOMM)Hmgu
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 7.63E-6
Vps13c
Vps13ctm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.12E-5
Ddost
Ddosttm1.1(KOMP)Vlcg
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.58E-5
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.61E-5
Nutm1
Nutm1tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.63E-5
Mrap2
Mrap2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.09E-5
Trappc10
Trappc10tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.09E-5
Pld3
Pld3tm1e(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.14E-5
Cand2
Cand2tm1a(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.47E-5
4930591A17Rik
4930591A17Riktm1a(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.58E-5
Wrap53
Wrap53tm1b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.69E-5
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.77E-5
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.14E-5
Retreg3
Retreg3tm2b(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.62E-5
Ampd2
Ampd2tm1b(EUCOMM)Hmgu
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.87E-5
Dact3
Dact3tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.92E-5
Notch3
Notch3tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 4.96E-5
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 7.57E-5
Wars
Warstm1b(EUCOMM)Hmgu
HET Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 8.63E-5
Sbno1
Sbno1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 9.22E-5
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 9.37E-5

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