Phenotype: increased red blood cell distribution width

Definition higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism

Synonyms
  • high RDW
  • high RDW
  • high red blood cell distribution width
  • high red blood cell distribution width
  • increased red blood cell size variability
  • increased erythrocyte distribution width
Show more
Related
Synonyms
  • Anisocytosis
  • Anisocytosis
  • anisocytosis
  • anisocytosis

MP browserMP:0010067

Phenotype associations stats

1.88% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased red blood cell distribution width (55/2928)

1.13% females (32/2830) 1.88% males (54/2865)



Gene variants with increased red blood cell distribution width

Total number of significant genotype-phenotype associations: 88

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Irgm1
Irgm1em1(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 0.0
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 0.0
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.99E-30
Fbxo38
Fbxo38em2(IMPC)Marc
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.44E-15
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.37E-15
Herc1
Herc1em3(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.0E-14
Prkab1
Prkab1em2(IMPC)Mbp
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 2.16E-13
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.83E-13
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.32E-12
Mul1
Mul1em1(IMPC)H
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 5.05E-12
Pdzd8
Pdzd8tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 7.04E-12
Klk14
Klk14tm1.1(KOMP)Vlcg
HOM Female postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.39E-10
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.98E-10
Etaa1
Etaa1em1(IMPC)Marc
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.27E-9
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.79E-9
Crlf3
Crlf3em1(IMPC)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.97E-9
Hbb-bh2
Hbb-bh2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width RBRC | IMPC 9.13E-9
Becn1
Becn1tm1b(KOMP)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.12E-8
Hpf1
Hpf1em1(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.15E-8
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.28E-8
Tbc1d22a
Tbc1d22atm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.63E-8
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 8.34E-8
Kat2b
Kat2bem1(IMPC)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.43E-7
Galnt18
Galnt18tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.96E-7
Atp5e
Atp5etm1b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.6E-7
3830406C13Rik
3830406C13Riktm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.79E-7
Klhl42
Klhl42tm1b(EUCOMM)Hmgu
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.51E-7
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.13E-6
Sgsm1
Sgsm1tm1b(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.59E-6
Sdc4
Sdc4tm2b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.61E-6
Micu2
Micu2tm1a(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.65E-6
Rreb1
Rreb1tm1b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.75E-6
Lpin2
Lpin2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 3.92E-6
Fbxo11
Fbxo11tm2b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 5.3E-6
Ninj2
Ninj2tm1a(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.7E-6
Angptl4
Angptl4tm1b(EUCOMM)Hmgu
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 7.63E-6
Vps13c
Vps13ctm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.46E-5
Ddost
Ddosttm1.1(KOMP)Vlcg
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.58E-5
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.61E-5
Nutm1
Nutm1tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.63E-5
Mrap2
Mrap2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.09E-5
Trappc10
Trappc10tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.09E-5
Pld3
Pld3tm1e(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.14E-5
Cand2
Cand2tm1a(EUCOMM)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.47E-5
4930591A17Rik
4930591A17Riktm1a(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.58E-5
Wrap53
Wrap53tm1b(EUCOMM)Wtsi
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.69E-5
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.77E-5
Klk5
Klk5tm2b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 2.84E-5
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.22E-5
Ampd2
Ampd2tm1b(EUCOMM)Hmgu
HET Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.87E-5
Dact3
Dact3tm1b(KOMP)Wtsi
HOM Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.92E-5
Retreg3
Retreg3tm2b(EUCOMM)Wtsi
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.24E-5
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 7.79E-5
Wars
Warstm1b(EUCOMM)Hmgu
HET Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 8.63E-5
Sbno1
Sbno1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 9.48E-5
Pstpip2
Pstpip2em1(IMPC)Tcp
HOM Female Male postnatal increased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 9.76E-5

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