Phenotype: abnormal otic vesicle morphology

Definition
any structural anomaly of the paired sacs of invaginated ectoderm that develop into the membraneous labyrinth of the inner ear
Synonyms
abnormal auditory vesicle morphology,  abnormal otocyst morphology,  abnormal acoustic vesicle morphology
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal otic vesicle morphology

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Alg10b
Alg10btm1.1(KOMP)Vlcg
HOM E9.5 abnormal otic vesicle morphology Otic vesicle morphology
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Krit1
Krit1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal otic vesicle morphology Otic vesicle morphology
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Pcnp
Pcnpem1(IMPC)Mbp
HOM E9.5 abnormal otic vesicle morphology Otic vesicle morphology
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Pigq
Pigqtm2b(EUCOMM)Wtsi
HOM E9.5 abnormal otic vesicle morphology Otic vesicle morphology
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Tbx20
Tbx20em1(IMPC)Mbp
HOM E9.5 abnormal otic vesicle morphology Otic vesicle morphology
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Uqcc3
Uqcc3em1(IMPC)Bay
HOM E9.5 abnormal otic vesicle morphology Otic vesicle morphology
Gross Morphology Embryo E9.5
BCM
IMPC
0.00

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 The way we measure

 Phenotype associations stats

0.80% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal otic vesicle morphology (6/751)

1.76% females (6/341) 1.17% males (4/341)

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